Table 1: Top ten KEGG pathways associated with differentially expressed or GO enriched genes.

KEGG metabolic pathways Differentially expresseda #Seq/#Enz GO enrichedb #Seq/#Enz Order of abundancec
30°C
Tryptophan metabolism 25/14 25/14 1/1/7d
Fatty acid degradation 23/10 23/10 2/2/10
Butanoate metabolism 21/14 21/14 3/3/25
Valine, leucine and isoleucine degradation 20/14 20/14 4/4/32
Tyrosine metabolism 20/14 20/14 5/5/9
Phenylalanine metabolism 19/15 19/15 6/6/8
Fatty acid biosynthesis 18/5 18/5/td> 7/7/35
Propanoate metabolism 18/11 18/11 8/8/33
Biosynthesis of unsaturated fatty acids 17/4 17/4 9/9/38
Metabolism of xenobiotics by cytochrome P450 17/6 17/6 10/10/19
-
37°C
Starch and sucrose metabolism 9/10 -- 1/--/2
Phenylalanine, tyrosine and tryptophan biosynthesis 9/15 5/12 2/7/44
Arginine and proline metabolism 8/11 6/9 3/1/5
Glycine, serine and threonine metabolism 8/4 6/3 4/2/3
Alanine, aspartate and glutamate metabolism 7/8 6/7 5/3/21
Purine metabolism 6/3 -- 6/--/1
Tryptophan metabolism 6/5 -- 7/--/7
Valine, leucine and isoleucine biosynthesis 5/3 5/3 8/4/61
Nitrogen metabolism 5/6 4/5 9/8/34
Pantothenate and CoA biosynthesis 5/3 5/3 10/5/43
Histidine metabolism -- 5/5 --/6/53
Butanoate metabolism -- 4/2 --/9/25
Phenylalanine metabolism -- 4/6 --/10/8


a: 849 annotated sequences at 30°C and 473 annotated sequences at 37°C were used in the KEGG pathway analysis.

b: 698 annotated sequences at 30°C and 158 annotated sequences at 37°C were used in the KEGG pathway analysis.

c: see Table S1 for ordered gene abundance for all 129 KEGG pathways of A. flavus.

d: order of abundance of differentially expressed genes/GO enriched genes/whole genome gene reference.