Table 1: Sample demographic and clinical characteristics (n= 37,972).

Characteristics

Controls (n = 23,447) N (%)

Invasive Cases (n = 14,525) N (%)

p-value2

Age (years)

Mean SD

 

55.6 11.9

 

58.1 11.3

 

<. 0001

< 40

2027 (8.7)

748 (5.2)

<. 0001

40-49

4771 (20.6)

2544 (17.6)

 

50-59

7403 (31.9)

4537 (31.3)

 

60-69

6098 (26.3)

4324 (29.8)

 

≥ 70

2892 (12.5)

2343 (16.2)

 

Family history of ovarian cancer1

 

 

 

No

15425 (92.0)

8634 (82.4)

<. 0001

Yes

1351 ( 8.0)

1849 (17.6)

 

Age at menarche (years)

 

 

 

Mean SD

12.9 1.7

12.8 1.6

0.0314

< 12

3128 (19.3)

1856 (19.2)

0.0772

12

3602 (22.2)

2257 (23.4)

 

13

4357 (26.9)

2621 (27.1)

 

≥ 14

5112 (31.6)

2923 (30.3)

 

Body mass inde (kg/m2)

 

 

 

< 25

3834 (48.2)

2528 (45.1)

0.0006

25-29

2332 (29.3)

1681 (30.0)

 

≥ 30

1797 (22.6)

1396 (24.9)

 

Oral contraceptive use

 

 

 

No

6136 (37.5)

4203 (43.7)

<. 0001

Yes

10230 (62.5)

5419 (56.3)

 

Histological subtypes

N/A

 

 

Serous

 

8369 (57.6)

 

Endometroid

 

2067 (14.2)

 

Clear Cell

 

1024 ( 7.1)

 

Mucinous

 

943 ( 6.5)

 

Others3

 

2122 (14.6)

 

 

1for the first degree relatives

2t-test for a continuous variable and chi-square test for a categorical variable

3Include mi ed cell, other specified epithelial, undifferentiated, unknown (but known to be epithelial), nonepithelial, other or unknown if epithelial, or missing