Table 2: Genotypic and Allele Frequency of MnSOD Single Nucleotide Polymorphisms (SNPs) in control group and Type 2 Diabetes Mellitus patients (T2DM). Chi-square test was used to determine significance at p < 0.05.

 

 

Control  (n = 40)

T2DM (n = 59)

p-Value

OR (95% CI)

Rs480 Genotype

 

 

< 0.001

4.068 (1.528-10.832)*

CC (Ala)  (n = 16)

10 (62.5%)

6 (37.5%)

CT (Ala/Val) (n = 55)

26 (47.3%)

29 (52.7%)

TT (Val)  (n = 28)

4 (14.3%)

24 (85.7%)

Allele

 

 

f(C)

57.50%

34%

f(T)

42.50%

66%

 

 

 

 

 

 

 

 

 

*Risk was calculated for a Val homozygote carrier