Table 5: Association of MnSOD Ala16Val polymorphism with Diabetic retinopathy, nephropathy and cardiovascular complications. Chi-square test was used to determine significance at P < 0.05.

 

Type 2 diabetic patients

Genotype

p-Value

OR (95% CI)

CC (Ala) (n = 6)

CT (Ala/Val) (n = 29)

TT (Val) (n = 24)

DR+ (n = 16)

1/16 (6.3%)

5/16 (31.3%)

10/16 (62.5%)

0.115

1.92  (1.082-3.84)

DR- (n = 43)

5/43 (11.6%)

24/43 (55.8%)

14/43 (32.6%)

DP+ (n = 5)

0/5 (0%)

2/5 (40%)

3/5 (60%)

0.563

1.543 (0.7-3.39)

DP- (n = 56)

6/56 (11.1%)

27/56 (50%)

21/56 (38.9%)

CVD+ (n = 8)

0/8 (0%)

3/8 (37.5%)

5/8 (62.5 %)

0.320

1.678 (0.881-3.995)

CVD- (n = 51)

6/51 (11.8%)

26/51 (51%)

19/51 (37.3%)

 

DR+: presence of diabetic retinopathy; DR-: no diabetic retinopathy; DP+: presence of nephropathy; DP-: no nephropathy; CVD+: presence of cardiovascular complications; CVD-: no cardiovascular complications.