Table 2: Univariate analysis and multiple regression analysis of associations between selected variables and 30-day mortality.
Univariate analysis | Multiple regression analysisa | |||
OR (95% CI) | P value | OR (95% CI) | P value | |
Age | 1.06 (1.03-1.09) | < 0.001 | 1.06 (1.02-1.09) | 0.001 |
Male sex | 0.65 (0.45-0.96) | 0.028 | 0.74 (0.46-1.17) | 0.19 |
Charlson index | 1.12 (1.03-1.21) | 0.008 | 1.08 (0.98-1.20) | 0.11 |
Pitt severity score | 1.78 (1.57-2.02) | < 0.001 | 1.84 (1.60-2.11) | < 0.001 |
Site of sepsis origin | 0.002 | 0.002 | ||
UTI | 2.75 (1.24-6.12) | 0.01 | 3.11 (1.22-7.96) | |
RTI | 1.4 (0.61-3.21) | 0.43 | 1.63 (0.62-4.30) | |
Other | 3.05 (1.17-7.91) | 0.02 | 3.56 (1.17-10.87) | |
Unknown | 1 | 1 | 1 | |
Non-CRB vs. CRB | 1.54 (0.98-2.4) | 0.053 | 1.11 (0.64-1.90) | 0.71 |
Aetiology of sepsis | 0.47 | 0.45 | ||
Identified, ESBL-E | 0.8 (0.5-1.28) | 0.34 | 1.05 (0.55-2.00) | |
Identified, not ESBL-E | 1.06 (0.69-1.64) | 0.78 | 1.37 (0.81-2.31) | |
Unidentified | 1 | 1 | 1 |
OR: odds ratio; CI: confidence interval; RTI: respiratory tract infection; UTI: urinary tract infection; CRB: carbapenem; ESBL-E: extended-spectrum β-lactamase-producing Enterobacteriaceae.
aThe value of the intercept in the multivariable model was -7.90.