Table 1: Summary of clinical features of LGI-1 autoimmune encephalitis present in both cases compared to the prevalence of clinical features in four other studies of anti- LGI1 encephalitis.

Clinical Features of Anti- LGI1 Encephalitis

Case 1

Case 2

Lai et al., 20101

Sonderen et al., 20169

Wang et al., 20172

Qiao et al., 20217

Number of patients

1

1

57

38

11

117

Subacute cognitive decline

+

+

100%

97%

100%

70%

Psychiatric disorder

+

+

Not mentioned

90%

45.5%

31.6%

Hyponatraemia

+

+

60%

65%

45.5%

65%

Seizure

-

-

82%

90%

54.5%

51.2%

Faciobrachial dystonic seizures

+

-

Not mentioned

47%

72.7%

35.9%

Favourable outcome

(mRS 0-2)

-

+

78%

67%

100%

100%