Table 1: Summary of clinical features of LGI-1 autoimmune encephalitis present in both cases compared to the prevalence of clinical features in four other studies of anti- LGI1 encephalitis.
Clinical Features of Anti- LGI1 Encephalitis |
Case 1 |
Case 2 |
Lai et al., 20101 |
Sonderen et al., 20169 |
Wang et al., 20172 |
Qiao et al., 20217 |
Number of patients |
1 |
1 |
57 |
38 |
11 |
117 |
Subacute cognitive decline |
+ |
+ |
100% |
97% |
100% |
70% |
Psychiatric disorder |
+ |
+ |
Not mentioned |
90% |
45.5% |
31.6% |
Hyponatraemia |
+ |
+ |
60% |
65% |
45.5% |
65% |
Seizure |
- |
- |
82% |
90% |
54.5% |
51.2% |
Faciobrachial dystonic seizures |
+ |
- |
Not mentioned |
47% |
72.7% |
35.9% |
Favourable outcome (mRS 0-2) |
- |
+ |
78% |
67% |
100% |
100% |