Table
1: Comparison
between SPRINT and HYVET.
Column
1 |
SPRINT |
HYVET |
Mean baseline age |
67.9 |
83.6 |
Baseline seated BP |
139.7/78.1 |
173.0/90.8 |
Target blood pressure |
120/80 |
150/80 |
BP difference between experimental
and control group |
14.8/7.6 |
15.0/6.1 |
Primary outcome |
Reduced events |
Reduced events |
Median frailty index |
0.18 |
0.17 |
Medication |
thiazide-type diuretics, calcium
channel blockers (CCBs), angiotensin converting enzyme (ACE) inhibitors,
angiotensin receptor blockers (ARBs) |
low dose diuretic (indapamide sustained release 1.5 mg daily) and additional
ACE inhibitor (perindopril) |
Physician discretion with
prescription medication |
yes |
no |