Metabolic and cardiovascular variables

Table 1: Metabolic and cardiovascular variables

Variable	WKY	FFR	SHR	FFHR	FFHR+Mtx
Fasting glucose (mmol/L)	4.88 ± 0.1	6.44 ± 0.2^*	5.0 ± 0.2	6.5 ± 0.2^{*^}	5.0 ± 0.1^**
Fasting triglycerides (mmol/L)	0.8 ± 0.0	1.9 ± 0.0^*#	1.0 ± 0.0	1.9 ± 0.1^*#	0.9 ± 0.2^**
HOMA (μU/mL insulin x mmol/L glucose)/22.5	4.00 ± 0.2	11.0 ± 0.1^*#	7.1 ± 0.15^*	15.1 ± 0.5^{*#^}	4.50 ± 0.5^**
Area under glucose tolerance test curve (mmol /L/90 min)	881 ± 64	1352 ± 21^*#	1300 ± 35^*	1909 ± 51^{*#^}	1005 ± 67^**
HDL cholesterol (mg/dl)	21.5 ± 0.3	13.2 ± 0.4^*#	19 ± 1.0^*	11.6 ± 1.5^{*#^}	18.2 ± 1.3^**
High-sensitivity C reactive protein (mg/dL)	1.5 ± 0.1	3.5 ± 0.0	3.1 ± 0.1	4.5 ± 0.1^{*#^}	0.9 ± 0.3^**
Systolic blood pressure (mmHg)
Baseline	105 ± 3	102 ± 1.0	103 ± 1	105 ± 3	105 ± 2
6 weeks	110 ± 1.0	129 ± 2.0^*	165 ± 2^*	172 ± 3^*#	170 ± 3^*
12 weeks	115 ± 1.3	139 ± 3.0^*	178 ± 1^*#	185 ± 2^{*#^}	135 ± 1.7^**

The above values correspond to metabolic and cardiovascular variables. Symbols indicate: ^*p < 0.001 vs. WKY; ^p < 0.001 vs. SHR; #p < 0.01 vs. FFR. ^** vs. FFHR.