Table 2: Oxidative stress and morphometric variables.
Variable | WKY | FFR | SHR | FFHR | FFHR+Mtx |
NAD(P)H oxidase activity (counts/min/mg tissue) | 40.5 ± 6 | 133 ± 5* | 160 ± 9.1*# | 297 ± 9.1*#^ | 41 ± 5.1*^** |
TBARS (μmol/L) | 1 ± 0.1 | 2.2 ± 0.1* | 1.69 ± 0.1* | 2.8 ± 0.1*#^ | 1.0 ± 0.7#^** |
Relative heart weight (mg/100 g body weight) | 225 ± 4 | 290 ± 4* | 330 ± 1.8*# | 400 ± 4*#^ | 290 ± 4** |
Myocardiocyte area (μm2) | 1682 ± 69 | 2066 ± 57* | 2222 ± 78*# | 3242 ± 55*#^ | 1688 ± 34** |
Lumen/media relationship in mesenteric arteries | 13.9 ± 0.3 | 10.2 ± 0.5* | 8.9 ± 0.6*# | 8.45 ± 0.2*# | 14.8 ± 2** |
The above values correspond to oxidative stress and morphometric variables. Symbols indicate: *p < 0.001 vs. WKY; ^p < 0.001 vs. SHR; #p < 0.01 vs. FFR. ** vs FFHR.