Table 4: Final model of multiple logistic regression of factors associated with CMV seroprevalence in children 3-5 years of age in the USA.

Variable

Adjusted OR (95% CI)

P Value

Breastfeeding (any vs none)

3.34 (1.85-6.05)

< 0.001

Birthweight in gm (less 1500 vs 1500+)

3.93 (0.256-60.43)

0.373

Age of child in years (4-5 vs 3)

1.96 (1.03-3.70)

0.042

Race (non-White vs White)

1.54 (0.96-2.45)

0.059

Cotinine Levels in ng/mL (0.05 vs 0.05+)

0.67 (0.0.44-1.02)

0.062

In this final model, breastfeeding was the most significant predictor of CMV seroprevalence. Breastfed children at any time post-delivery were 2+ times more likely to be CMV sero +ve as compared to their non-breastfed counterparts. As measured by cotinine levels, children not exposed to tobacco/E-cigarettes were 0.7 times less likely to be CMV sero +ve as compared to their unexposed counterparts (P = 0.062).