Table 1: Susceptibility and MIC result of colonized
isolates of H. influenza.
|
Antibiotic
used |
All
H. influenzae (n=121) |
No.
(%) of strains |
Break point value (µgml-1) |
|||||
|
MIC50 (µgml-1) |
MIC90 (µgml-1) |
MIC
range (µgml-1) |
All H. influenza (n = 121) |
H. influenzae type b (Hib) (n = 18) |
Non-Hib (n = 103) |
S |
R |
|
|
Ampicillin |
0.25 |
64 |
0.12-
>256 |
21 (17.4) |
12
(66.7) |
9 (8.7) |
≤ 1 |
> 1 |
|
Amoxicillin |
1.0 |
128 |
0.25-
>256 |
21 (17.4) |
12
(66.7) |
9 (8.7) |
≤ 2 |
> 2 |
|
*Azithromycin |
2.0 |
4 |
0.5-8.0 |
1 (0.83) |
0
(0) |
1 (1) |
≤ 4 |
> 4 |
|
Chloramphenicol |
0.5 |
8 |
0.25- >32 |
26 (21.5) |
13
(72.2) |
13 (12.6) |
≤ 2 |
> 2 |
|
Cotrimoxazole |
8.0 |
≥ 32 |
0.032- >32 |
66 (54.8) |
16
(88.9) |
50 (48.6) |
≤ 0.5 |
> 1 |
|
Ciprofloxacin |
0.004 |
0.016 |
≤ 0.002-0.016 |
0 (0) |
0
(0) |
0 (0) |
≤ 0.5 |
> 0.5 |
|
Gatifloxacin |
0.008 |
0.016 |
0.004-0.016 |
0 (0) |
0
(0) |
0 (0) |
≤ 0.5 |
> 0.5 |
|
Levofloxacin |
0.008 |
0.032 |
0.004-0.032 |
0 (0) |
0
(0) |
0 (0) |
≤ 1 |
> 1 |
|
Moxifloxacin |
0.016 |
0.032 |
0.008-0.032 |
0 (0) |
0
(0) |
0 (0) |
≤ 1 |
> 1 |
|
Ceftriaxone |
≤ 0.016 |
≤ 0.016 |
≤ 0.016 |
0 (0) |
0
(0) |
0 (0) |
≤ 0.125 |
> 0.125 |
* Break point of azithromycin
when incubated in CO2