Table 2: Host-related predictors of persistence of hepatitis C virus infection in the Egyptian population obtained by univariate analysis.
Host risk factor |
Spontaneous cure n = 257 |
Persistent infection n = 802 |
Crude OR |
95% CI |
p-value |
|||
No |
% |
No |
% |
|||||
Gender |
Female® |
157 |
27.7 |
410 |
72.3 |
1.50 |
(1.13-2.00) |
0.01 |
Male |
100 |
20.3 |
392 |
79.7 |
||||
Age |
<45® |
77 |
31.0 |
171 |
69.0 |
1.58 |
(1.15-2.16) |
0.00 |
45+ |
180 |
22.2 |
631 |
77.8 |
||||
Residence |
Urban® |
55 |
24.8 |
167 |
75.2 |
1.04 |
(0.73-1.46) |
0.84 |
Rural |
202 |
24.3 |
635 |
75.7 |
||||
Education |
Illiterate/able to read and write |
133 |
17.9 |
610 |
82.1 |
3.26 |
(2.00-5.33) |
0.00 |
Basic |
24 |
23.1 |
80 |
76.9 |
2.37 |
(1.25-4.51) |
0.01 |
|
Secondary |
68 |
31.6 |
147 |
68.4 |
1.54 |
(0.90-2.63) |
0.12 |
|
University degree or higher® |
32 |
41.6 |
45 |
58.4 |
- |
- |
- |
|
Marital status |
Never married® |
4 |
28.6 |
10 |
71.4 |
1.25 |
(0.39-4.03) |
0.71 |
Ever married |
253 |
24.2 |
792 |
75.8 |
||||
Risk of occupation |
No® |
233 |
26.6 |
642 |
73.4 |
2.42 |
(1.54-3.81) |
0.00 |
Yes |
24 |
13.0 |
160 |
87.0 |
||||
Experience working abroad |
No® |
204 |
23.8 |
652 |
76.2 |
0.89 |
(0.62-1.26) |
0.50 |
Yes |
53 |
26.1 |
150 |
73.9 |
||||
Tattooing |
No® |
245 |
24.6 |
751 |
75.4 |
1.39 |
(0.73-2.64) |
0.32 |
Yes |
12 |
19.0 |
51 |
81.0 |
||||
Ear/body piercing |
No® |
161 |
25.5 |
471 |
74.5 |
1.18 |
(0.88-1.57) |
0.27 |
Yes |
96 |
22.5 |
331 |
77.5 |
||||
Sharing sharp instruments |
No® |
59 |
22.3 |
205 |
77.7 |
0.87 |
(0.62-1.21) |
0.40 |
Yes |
198 |
24.9 |
597 |
75.1 |
||||
Using barber tools |
No® |
102 |
23.0 |
341 |
77.0 |
0.89 |
(0.67-1.18) |
0.42 |
Yes |
155 |
25.2 |
461 |
74.8 |
||||
Pierced with blood-contaminated tool |
No® |
238 |
24.5 |
732 |
75.5 |
1.20 |
(0.71-2.03) |
0.50 |
Yes |
19 |
21.3 |
70 |
78.7 |
||||
Being bitten by an animal |
No® |
205 |
24.1 |
646 |
75.9 |
0.95 |
(0.67-1.35) |
0.78 |
Yes |
52 |
25.0 |
156 |
75.0 |
||||
Exposed to blood |
No® |
197 |
24.1 |
622 |
75.9 |
0.95 |
(0.68-1.33) |
0.76 |
Yes |
60 |
25.0 |
180 |
75.0 |
||||
Blood/blood product transfusion |
No® |
221 |
24.7 |
675 |
75.3 |
1.16 |
(0.77-1.72) |
0.48 |
Yes |
36 |
22.1 |
127 |
77.9 |
||||
Invasive procedure |
No® |
174 |
23.5 |
565 |
76.5 |
0.88 |
(0.65-1.19) |
0.40 |
Yes |
83 |
25.9 |
237 |
74.1 |
||||
Acupuncture |
No® |
245 |
23.5 |
797 |
76.5 |
0.13 |
(0.04-0.37) |
0.00 |
Yes |
12 |
70.6 |
5 |
29.4 |
||||
History of jaundice |
No® |
236 |
24.4 |
732 |
75.6 |
1.07 |
(0.65-1.80) |
0.78 |
Yes |
21 |
23.1 |
70 |
76.9 |
||||
Circumcision |
No® |
44 |
41.1 |
63 |
58.9 |
2.42 |
(1.60-3.67) |
0.00 |
Yes |
213 |
22.4 |
739 |
77.6 |
||||
Blood sampling |
No® |
25 |
20.5 |
97 |
79.5 |
0.78 |
(0.49-1.25) |
0.30 |
Yes |
232 |
24.8 |
705 |
75.2 |
||||
Frequent dentist visits |
No® |
118 |
29.0 |
289 |
71.0 |
1.51 |
(1.13-2.00) |
0.00 |
Yes |
139 |
21.3 |
513 |
78.7 |
||||
Previous hospitalization |
No® |
128 |
23.5 |
417 |
76.5 |
0.92 |
(0.69-1.21) |
0.54 |
Yes |
129 |
25.1 |
385 |
74.9 |
||||
Delivery at home |
No® |
150 |
22.6 |
515 |
77.4 |
0.78 |
(0.59-1.04) |
0.09 |
Yes |
107 |
27.2 |
287 |
72.8 |
||||
Schistosomiasis |
No® |
123 |
28.2 |
313 |
71.8 |
1.43 |
(1.08-1.90) |
0.01 |
Yes |
134 |
21.5 |
489 |
78.5 |
||||
PAT |
No® |
153 |
27.2 |
410 |
72.8 |
1.41 |
(1.06-1.87) |
0.02 |
Yes |
104 |
21.0 |
392 |
79.0 |
||||
Genital ulcers |
No® |
181 |
24.0 |
574 |
76.0 |
0.95 |
(0.69-1.29) |
0.72 |
Yes |
76 |
25.0 |
228 |
75.0 |
||||
History of oral ulcers |
No® |
185 |
28.3 |
469 |
71.7 |
1.82 |
(1.34-2.48) |
0.00 |
Yes |
72 |
17.8 |
333 |
82.2 |
||||
Incarceration |
No® |
257 |
24.8 |
781 |
75.2 |
14.17 |
(0.86-234.73) |
0.06 |
Yes |
0 |
0.0 |
21 |
100.0 |
||||
Previous stay at camps/youth homes |
No® |
141 |
21.5 |
515 |
78.5 |
0.68 |
(0.51-0.90) |
0.01 |
Yes |
116 |
28.8 |
287 |
71.2 |
||||
Fatigue during the last 6 months |
No® |
174 |
27.3 |
463 |
72.7 |
1.53 |
(1.14-2.07) |
0.00 |
Yes |
83 |
19.7 |
339 |
80.3 |
||||
Opioid injections |
No® |
251 |
24.0 |
793 |
76.0 |
0.47 |
(0.17-1.35) |
0.16 |
Yes |
6 |
40.0 |
9 |
60.0 |
||||
Alcohol consumption |
No® |
241 |
24.3 |
749 |
75.7 |
1.07 |
(0.60-1.90) |
0.83 |
Yes |
16 |
23.2 |
53 |
76.8 |
||||
Shisha smoking |
No® |
213 |
25.4 |
627 |
74.6 |
1.35 |
(0.94-1.95) |
0.11 |
Yes |
44 |
20.1 |
175 |
79.9 |
||||
Family history of hepatic disease |
No® |
209 |
23.9 |
666 |
76.1 |
0.90 |
(0.62-1.28) |
0.53 |
Yes |
48 |
26.1 |
136 |
73.9 |
||||
Partner with STIs |
No® |
241 |
23.6 |
780 |
76.4 |
0.42 |
(0.22-0.82) |
0.01 |
Yes |
16 |
42.1 |
22 |
57.9 |
||||
Partner infected with HCV |
No® |
249 |
24.9 |
751 |
75.1 |
2.11 |
(0.99-4.52) |
0.05 |
Yes |
8 |
13.6 |
51 |
86.4 |
||||
Contact with jaundiced person |
No® |
239 |
25.0 |
716 |
75.0 |
1.59 |
(0.94-2.71) |
0.08 |
Yes |
18 |
17.3 |
86 |
82.7 |
||||
Sex during menstruation |
No® |
248 |
24.6 |
762 |
75.4 |
1.45 |
(0.69-3.02) |
0.33 |
Yes |
9 |
18.4 |
40 |
81.6 |
PAT: Parenteral antischistosomal therapy; STIs: Sexually transmitted infections; ®: Reference category.