Table 1: Demographic and clinical characteristics of patients per treatment group, at enrolments (Day 0) CAMEROON DC, 2012-2013.

Characteristics

AL (N = 72)

ASMQ (N = 72)

DHAP (N = 72)

P (1)

P (2)

Mean Age (months) SD

32.97 (16.4)

37.90 (16.7)

42.8 (14.6)

0.15

0.15

Mean Weight (Kg) SD

12.9 (2.8)

13.7 (3.1)

14.4 (2.6)

0.47

0.19

Sex-ratio Male/Female

1.8 (44/28)

1 (36/36 )

0.8 (32/40)

 

 

Mean Temperature (°C). SD (Range)

38.1 (1.1)

(36-41)

38.4 (1.0)

(36.03-40.08)

38.2 (1.0)

(36.7-40.6)

0.50

0.13

Mean temperature ≥ 38 °C (°C). SD (Range)

39.1 (1.0)

(38-41)

38.97 (0.8)

(38-40.8)

38.8 (0.9)

(38-39.8)

0.51

0.45

Mean temperature < 38 SD (Range)

37.3 (0.45)

(36-37.9)

37.4 (0.4)

(36.3-37.9)

37.4 (0.4)

(36.7-37.9)

0.70

0.90

Proportion ≥ to 40 °C SD (range)

40.3 (0.3)

(40-41)

40.2 (0.3)

(40-40.2)

40.17 (0.2)

(40-40.6)

0.23

0.90

Geometrical mean Parasite density(p/ul) SD (*CI%95)

27,061

(-6074-22192)

25135 (-13627-1747)

19002 (-6074-22192)

0.09

0.65

Geometrical mean ≥ 100,000 (P/ul) SD(CI%95)

198849.8 (-1840.5-138198.6)

185500.3 (-30969.6-140628.8)

130670.7 (-1840.5-38198.6)

0.5

0.2

Mean Hematocrite(%) SD (P > 0.05)

33.2 (6.0)

32.8 (6.0)

33.8 (5.9)

0.56

0.13

Anaemia between 15% et 29%

23/72 (31.9%)

28/72 (38.9%)

19/72 (28.4)

 

 

*Confidence interval at 95% (binomial exact method). (1) Compare DHAP vs. AL. (2) Compare DHAP vs. ASMF.