Table 2: Baseline inflammatory markers and hematologic indices of patients with non-severe and severe COVID-19.

 

Total

Non severe

Severe

P-value

N = 1368

n = 845

n = 523

Inflammatory Markers

       

C-Reactive Protein (mg/dL)

6.64 ± 33.50

2.48 ± 21.07

13.32 ± 46.29

< 0.01

Serum Ferritin (ng/mL)

537.84 ± 499.04

305.29 ± 319.29

914.04 ± 508.79

< 0.01

Serum LDH (U/L)

700.04 ± 571.49

526.56 ± 290.83

979.29 ± 768.31

< 0.01

Serum Procalcitonina (ng/mL)

3.94 ± 29.12

1.59 ± 18.28

6.16 ± 36.45

< 0.01

Hematologic Indices

 

 

 

 

Leukocyte Count (x103/µL)

9.18 ± 6.40

8.77 ± 3.46

9.81 ± 9.19

0.462

Neutrophil-to-Lymphocyte Ratio

5.11 ± 6.36

3.38 ± 4.73

7.75 ± 7.53

< 0.01

Fibrinogen (g/L)b

4.89 ± 1.74

3.79 ± 1.49

5.33 ± 1.64

< 0.01

D-dimer (µg/mL)c

1.69 ± 1.38

1.15 ± 1.18

1.92 ± 1.39

< 0.01

Non-normal distribution; variables are reported in Mean ± Standard Deviation for a large population (Central Limit Theorem), instead of Median with 25th and 75th interquartile ranges.

aNumber of COVID-19 patients who tested Procalcitonin was 421 and 443 in the non-severe and severe group, respectively.

bNumber of COVID-19 patients who tested Fibrinogen was 143 and 353 in the non-severe and severe group, respectively.

cNumber of COVID-19 patients who tested D-dimer was 147 and 354 in the non-severe and severe group, respectively.