Table 6: Optimal Cut-Off Values of the Potential Predictors with Sensitivity and Specificity as a Stand-alone Diagnostic.
|
Summary |
Optimal Cut-off |
Sensitivity (%) |
Specificity (%) |
AUROC |
Optimal Cut-Off Point |
|
Youden’s Index (%) |
|||||
|
CRP (mg/dL) |
1.85 mg/dL |
79 |
84 |
0.855a |
63.8 |
|
Ferritin (ng/mL) |
621.4 ng/mL |
71.3 |
74.8 |
0.804a |
46.1 |
|
LDH (U/L) |
644.85 U/L |
78.7 |
81.6 |
0.857a |
60.3 |
|
Procalcitonin (ng/mL) |
0.105 ng/mL |
78.7 |
68 |
0.763b |
46.7 |
|
Neutrophil-to- Lymphocyte Ratio |
4.32 |
59.7 |
78.6 |
0.740b |
38.3 |
|
Fibrinogen (g/L) |
4.7g/L |
70 |
67 |
0.739b |
37 |
aDiagnostic that has excellent discrimination (AUROC ≥ 0.8).
bDiagnostic that has acceptable discrimination (AUROC ≥ 0.8) - Clinician has the discretion to use or not.