Table 3: Category III medications with response rate, remission, time to remission and level of evidence.

Name

Overall response rate

Remission rate of symptoms in responders

% of responders achieving 100% or near 100% remission

Time to achieve 100% remission

Level of evidence

Nimodipine, a calcium blocker that improves blood flow in the brain [45]

60%

50%

Not documented

Hours - 6 months

II

Ampligen, a double-stranded mismatched molecule [46]

50%

10%-30%

Not documented

6 months

I

Dexedrine, a central nervous system stimulant [47]

90%

50%

Not documented

6 weeks

II

Isoprinosine, an analog of thymus hormones [48]

60%

17%

Not documented

3 months

II

D-Ribose, a monosaccharide [49]

66%

30%-50%

Not documented

3 weeks

II