Table 3: Category III medications with response rate, remission, time to remission and level of evidence.
Name |
Overall response rate |
Remission rate of symptoms in responders |
% of responders achieving 100% or near 100% remission |
Time to achieve 100% remission |
Level of evidence |
Nimodipine, a calcium blocker that improves blood flow in the brain [45] |
60% |
50% |
Not documented |
Hours - 6 months |
II |
Ampligen, a double-stranded mismatched molecule [46] |
50% |
10%-30% |
Not documented |
6 months |
I |
Dexedrine, a central nervous system stimulant [47] |
90% |
50% |
Not documented |
6 weeks |
II |
Isoprinosine, an analog of thymus hormones [48] |
60% |
17% |
Not documented |
3 months |
II |
D-Ribose, a monosaccharide [49] |
66% |
30%-50% |
Not documented |
3 weeks |
II |