Supplementary Table 3: Analysis of electrically evoked calcium transients in EDL and soleus muscles from chow and LVAD fed C57/Bl6 mice.
|
Muscle type |
Treatment (number fibers analyzed) |
∆F/F (mean ± SD) |
TTP ms (mean ± SD) |
HTTP ms (mean ± SD) |
HRT ms (mean ± SD) |
Twitch stimulation |
EDL |
Chow (n = 57) |
1.48 ± 0.21 |
1.46 ± 0.25 |
0.99 ± 0.20 |
2.07 ± 0.69 |
LVAD (n = 50) |
1.24 ± 0.19* |
1.34 ± 0.20* |
1.02 ± 0.19 |
1.81 ± 0.48 |
||
Soleus |
Chow (n = 29) |
0.65 ± 0.14 |
2.03 ± 0.37 |
1.28 ± 0.47 |
10.04 ± 1.98 |
|
LVAD (n = 28) |
0.60 ± 0.15 |
2.07 ± 0.47 |
1.33 ± 0.35 |
11.42 ± 2.57 |
||
Tetanic stimulation |
EDL |
Chow (n = 42) |
1.81 ± 0.30 |
|
|
|
LVAD (n = 46) |
1.60 ± 0.32* |
|
|
|
||
Soleus |
Chow (n = 27) |
1.29 ± 0.42 |
|
|
|
|
LVAD (n = 31) |
1.10 ± 0.32* |
|
|
|
*p < 0.05 Mann-Whitney test.