Table 2: Detailed description of the patients diagnosed with peripheral neuropathy.

Patient No.

TNSra

NCS

(Large Fiber Impairment)

SUDOSCAN

(Sudomotor Function)b

Patient #1

12

Axonal PSN

N/A

Patient #2

17

N/A

N/A

Patient #3

12

Axonal PSN

No dysfunction

Patient #4

12

N/A

N/A

Patient #5

21

Mixed SMN

No dysfunction

Patient #6

15

Mixed PSN

No dysfunction

Patient #7

12

Axonal PSN

N/A

Patient #8

10

N/A

Severe dysfunction

Patient #9

11

Mixed PSN

Moderate dysfunction

Patient #10

20

Mixed SMN

Moderate dysfunction

Patient #11

18

Axonal PSN

No dysfunction

Patient #12

13

Axonal PSN

Severe dysfunction

Patient #13

17

Axonal PSN

Moderate dysfunction

PSN: Pure Sensory Neuropathy (N/A = Not Available); NCS: Nerve Conduction Studies; SMN: Sensory Motor Neuropathy; Tnsr: Total Neuropathy Score Reduced

aScore 0 indicates no PN, scores 1-9 indicate moderate PN, score > 20 corresponds to severe PN.

bSkin conductance is measured microSiemens (µS). Normal sudomotor function corresponds to an interval of 60-100 µS, moderately reduced sudomotor function: 40-60 µS and severely reduced sudomotor function: 0-40 µS.