Table 2: Probable relationship of the proposed diet and mechanism of arsenic poisoning.

Arsenic poisoning

Mechanism

Diet factors

Counter mechanism

Oxidative stress

Oxidation reaction

Green tea, pointed gourd fruit, gooseberry fruit, Vitamin C, turmeric, Amaranthus leaves, E. alba leaves

Antioxidant

DNA damage

Dimethyl arsine peroxyl radical generation

Turmeric, skunkvine leaves, Amaranthus leaves, E. alba leaves

DNA repair

Keratosis

Over expression of epidermal keratinocytes

Vitamin B12, Vitamin C, turmeric, ginger, Amaranthus leaves, E. alba leaves

Chelation, DNA repair

Liver damage

Interaction with protein targets in hepatocytes

E. alba leaves, Moringa leaves, garlic, corn fruit, papaya fruit, pointed gourd fruit

Antioxidant, DNA repair

Kidney damage, albuminurea, proteinurea

Endothelial dysfunction

Moringa leaves, Amaranthus leaves, garlic, corn fruit, pointed gourd fruit

Antioxidant, DNA repair

Skin cancer, liver cancer

Unregulated proliferation (suppression of p53 pathway)

Turmeric, ginger, green tea, cumin seeds, E. alba leaves

Anticancer, antitumor, anti-inflammatory

Cardiovascular diseases, Atherosclerosis

Elevation of cell adhesion molecules,  Oxidized lipids formation

Garlic, ginger, Moringa leaves, green tea, skunkvine leaves

Antioxidant, DNA repair

Alzheimer’s, Parkinson’s disease

Dopamine quinone radicals formation

Turmeric, ginger, Moringa leaves

Antioxidant, DNA repair

Multiple organ failure

Necrotic cell death

Turmeric, ginger, green tea, Moringa leaves

Antioxidant, Anti-inflammatory