Table 3: The incidence and hazard ratio of coronary heart disease among patients with CRS who did and did not undergo surgery compared with patients without CRS.
|
Variable |
N |
Event |
PY |
Rate# |
Crude HR (95% CI) |
Adjusted HR† (95% CI) |
Crude HR (95% CI) |
Adjusted HR† (95% CI) |
|
CRS (-) |
54576 |
3337 |
370037 |
0.90 |
1.00 |
1.00 |
|
|
|
CRS (+) |
|
|
|
|
|
|
|
|
|
With surgery |
|
|
|
|
|
|
|
|
|
No |
11148 |
990 |
77377 |
1.28 |
1.42 (1.33-1.53)*** |
1.33 (1.24-1.43)*** |
1.00 |
1.00 |
|
Yes |
2496 |
183 |
15850 |
1.15 |
1.27 (1.10-1.48)** |
1.16 (1.00-1.35)* |
0.89 (0.76-1.05) |
0.88 (0.75-1.04) |
Rate#: incidence rate per 100 person-years.
Adjusted HR†: Multivariable analysis including age, sex, and comorbidities such as diabetes mellitus, hypertension, hyperlipidemia, asthma, stroke, chronic obstructive pulmonary disease, alcohol-related illness, and tobacco dependency.
*: P < 0.05, **: P < 0.01, ***: P < 0.001
CRS: Chronic Rhinosinusitis; PY: Person-Years; HR: Hazard Ratio; CI: Confidence Interval