Table 1: Published case reports of cyanoacrylate applications to the EAC and treatment details.

Study, Author (Year)

Number of cases

Solvent application

Duration

Intervention and adverse outcome (if any)

Khan, et al. [8]

1

Acetone under GA with no effect

Unspecified

Extraction under GA (dissection along plane)

Gogia & Agarwal [2]

1

Acetone under LA

1 minute

Extraction under LA

Dimitriadis, et al. [3]

3

Antibiotic ear drop

Not specified

Extraction under GA with TM perforation

None

-

Conservative: glue plug detached after a “few months”

None

-

Extracted under GA

Bala, et al. [6]

1

ichthammol glycerin without effect and then acetone

ichthammol glycerin: 1 hour

acetone: 30 minutes

Extraction under LA

Stasche, et al. (2008)

2

Hydrogen peroxide

Unspecified

Complete removal from left EAC; partial removal from right complicated by otitis externa and myringitis warranting surgery under GA

None

-

Extraction under GA (including tympanomeatal flap)

Ogunleye (2002)

1

Acetone

Unspecified

Unspecified

Persaud [9]

1

Warm peroxide (3%) - two pours

10 minutes × 2

Removal without analgesia

O’Donnell, et al. (1997)

 

 

 

 

Abadir, et al. (1995)

3

Acetone-soaked cotton wool ball placed over meatus

10 minutes

Careful extraction (no analgesia mentioned)

Acetone-soaked cotton wool ball placed over meatus

10 minutes

Careful extraction (no analgesia mentioned)

No solvent

-

Torn TM during removal under GA

Pollock (1988)

1

No solvent

-

Extraction under GA (piecemeal removal)

Wight and Bull [10]

1

No solvent

-

Extraction under GA (endaural incision)