Table 5: Effects of shea butter, non-saponifiable extract, saponifiable extract, Steroid extract, Cetirizine and xylometazoline in nasal congestion.
|
Variable |
Treatment Group |
|||||
|
Standard of Care Group |
Shea butter/ Shea butter extract |
|||||
|
|
Cetirizine
|
Xylometazoline
|
Non-Saponifiable |
Saponifiable
|
Shea Butter
|
Steroid
|
|
Number of Subjects |
8 |
6 |
7 |
7 |
8 |
6 |
|
Duration of Experiment (h) |
24 |
24 |
24 |
24 |
24 |
24 |
|
Dose |
10 mg |
2-3 dropsa |
2-4 g |
2-4 g |
2-4 g |
2-4 g |
|
Onset of action (min) |
5.0 |
1.0 |
0.5-1.5 |
0.5-1.5 |
1.5-5.0 |
1-5 |
|
Duration of action (h) |
5-6 |
2-4 |
> 4 |
> 4 |
5-8 |
> 4 |
|
Period from first dose till moderate to high congestion occurred (mins) |
30 |
30 |
20 |
30 |
30 |
30 |
|
Period from first dose till congestion ceased |
- |
48-72 |
12-24 |
12-24 |
12-24 |
- |
|
Number of Application of drugs during this period |
1 |
2 |
1 |
1 |
1 |
1 |
|
Nasal Discharge after usage |
No |
No |
Yes (Mucolytic) |
Yes |
Yes |
Yes |
|
Side Effects/Allergic reaction |
Dizziness |
Nasal Irritation |
Harsh |
Harsh |
None |
None |
a0.05 ml per drop