Table
1: Demographic,
clinical, and psychological characteristics of corticosteroid-naive SLE
patients vs. healthy controls.
|
Variables |
SLE
patients |
Controls |
p |
|
(N
= 43) |
(N
= 30) |
||
|
Demographics |
|||
|
Age, years |
28.7 (8.6) |
28.1 (6.7) |
0.822 |
|
Female |
41/42 (97.6) |
30/30 (100) |
> 0.999 |
|
Education, years |
13.4 (1.9) |
13.3 (1.7) |
0.963 |
|
Clinical characteristics |
|||
|
Disease duration, monthsa |
26.1 (40.9) |
NA |
|
|
Time since SLE diagnosis, months |
3.2 (18.3) |
NA |
|
|
Performance statusb |
0.4 (0.6) |
NA |
|
|
Pain, VAS, mm |
30.4 (24.0) |
NA |
|
|
Fatigue, VAS, mm |
33.0 (27.6) |
NA |
|
|
SLEDAI-2K |
11.9 (5.9) |
NA |
|
|
Profile of Mood State
(POMS) subscales |
|||
|
Tension-Anxiety |
14.1 (7.1) |
10.7 (5.8) |
0.043c |
|
Depression-Dejection |
13.9 (10.2) |
9.2 (7.2) |
0.045c |
|
Fatigue |
11.0 (6.2) |
10.5 (6.7) |
0.590 |
Data are number/number assessed (%) or mean (standard
deviation).
P
values were determined by Fisher's exact test or Mann-Whitney U-test.
aDefined as
the time between the onset of SLE-attributable symptoms and assessment
bDetermined
based on Eastern Cooperative Oncology Group criteria
cSignificant
variables
NA = Not Applicable
VAS = Visual Analog Scale
SLEDAI-2K = Systemic Lupus Erythematosus Disease Activity Index 2000