Table 3: Cumulative symptoms of SLEDAI-2K in corticosteroid-naive SLE patients
with vs. without fatigue.
|
Variables |
Fatigue, yes |
Fatigue, no |
p |
|
(n = 8) |
(n = 35) |
||
|
SLEDAI-2K itemsa |
|||
|
Visual disturbance |
0/8 (0%) |
1/35 (3%) |
> 0.999 |
|
Vasculitis
|
0/8 (0%) |
1/35 (3%) |
> 0.999 |
|
Arthritis |
7/8 (88%) |
19/35 (54%) |
0.088 |
|
Myositis |
0/8 (0%) |
1/35 (3%) |
> 0.999 |
|
Urinary casts |
1/8 (13%) |
7/35 (20%) |
0.533 |
|
Hematuria |
1/8 (13%) |
6/35 (17%) |
0.612 |
|
Proteinuria |
1/8 (13%) |
7/35 (20%) |
0.533 |
|
Pyuria |
2/8 (25%) |
4/35 (11%) |
0.308 |
|
New rash |
3/8 (38%) |
17/35 (49%) |
0.434 |
|
Alopecia |
1/8 (13%) |
6/35 (17%) |
0.612 |
|
Mucosal ulcers |
2/8 (25%) |
1/35 (3%) |
0.084 |
|
Pleurisy |
3/8 (38%) |
2/35 (6%) |
0.037b |
|
Pericarditis |
0/8 (0%) |
2/35 (6%) |
> 0.999 |
|
Low complement |
6/8 (75%) |
31/35 (89%) |
0.308 |
|
Increased DNA
binding |
6/8 (75%) |
30/35 (86%) |
0.388 |
|
Fever |
1/8 (13%) |
10/35 (29%) |
0.241 |
|
Thrombocytopenia |
1/8 (13%) |
3/35 (9%) |
0.576 |
|
Leukopenia |
4/8 (50%) |
11/35 (31%) |
0.275 |
Data are
number/number assessed (%).
P
values were determined by Fisher's exact tests.
aSignificant variables
bOther
SLEDAI-2K symptoms (seizure, psychosis, organic brain syndrome, cranial nerve
disorder, lupus headache, and cerebrovascular accident) were not found in any
patient.
SLEDAI-2K =
Systemic Lupus Erythematosus Disease Activity Index
2000