Table 1: Summary of the effects of GsCG and its components on the IL-1β stimulated C-20/A4 chondrocyte cell line.

 

GsCG

Gs

GR

Cu

NOX4 activity

++

-

++

++

ADAMTS5 pro-MMP1

++

++

-

-

++

-

++

++

Viability Caspase 3

++

++

-

-

++

++

-

++

HO-1

++

++

-

++

 

++ Significant impact; + Potential impact; No impact