Table 2: Cut-off value and diagnostic accuracy of urinary VCAM-1, KIM-1, and ET-1 in diagnosing LN.

Urinary Markers

Cut-off

value

Specificity

(%)

Sensitivity

(%)

PPV

(%)

NPV

(%)

VCAM-1

(ng/mg Cr)


3.6


71.7


66.7


69.3


46.7

KIM-1

(ng/mg Cr)


0.14


65.0


56.7


63.9


50.6

ET-1

(pg/mg Cr)


1.9


96.7


80.0


92.3


90.0

Abbreviations: Cr = Creatinine; PPV= Positive Predictive Value; NPV = Negative Predictive Value.