Table
2: Pregnancy outcomes in 109 women according to
disease subset and disease onset in systemic sclerosis.
|
All patients |
¶dcSSc #N0 (%) |
*lcSSc N0 (%) |
£0R (CI 95% CI) |
P-value |
After Disease onset N0 (%) |
Before disease onset N0 (%) |
£OR (CI 95%) |
P-valve |
Pregnancies |
|||||||||
Women with pregnancy |
109 |
52 |
57 |
- |
- |
18 |
71 |
- |
- |
No. of pregnancies |
278 |
123 |
155 |
- |
|
49 |
229 |
- |
- |
PREGNANCY OUTCOME |
|
|
|
|
|
|
|
|
|
Women with abortion |
32 (29) |
9 (17) |
23 (40) |
0.30
(0.1268 - 0.75) |
0.01 |
8:18 (44) |
24:71 (34) |
1.56 (0.54 - 4.48) |
0.40 |
Women with RPL |
10 (9) |
3 (5.7) |
7 (12.2) |
1.20 (0.27 - 5.24) |
0.80 |
2 (11) |
8 (11) |
0.64 (0.12 - 3.34) |
0.59 |
No. of abortions |
46 (16.5) |
14 (11.3) |
32 (21) |
0.49 (0.25 - 0.97) |
0.04 |
14 (29) |
32 (14) |
2.46 (1.19 - 5.07) |
0.01 |
No. of spontaneous abortions |
34 (12.2) |
11 (8.9) |
23 (14.8) |
0.56 (0.26 - 1.20) |
0.14 |
13 (26.5) |
22 (9.6) |
3.05 (1.39 - 6.69) |
0.005 |
No. of therapeutic abortions |
12 (4.3) |
3 (2.4) |
9 (5.8) |
0.41 (0.10 - 1.53) |
0.18 |
1 (2) |
10 (4.3) |
0.93 (0.19-4.39) |
0.92 |
Women with delivery |
102 (93.5) |
49 (94.2) |
53 (93.0) |
3.36 (0.66 - 16.98) |
0.14 |
12 (67.0) |
70 (98.0) |
0.02 (0.003 - 0.25) |
0.001 |
No. of deliveries |
227 (81.6) |
107 (87.0) |
120 (77.0) |
2.17 (1.14 - 4.12) |
0.10 |
33 (67.0) |
191 (83.3) |
0.41 (0.20 - 0.81) |
0.01 |
Twin pregnancy |
1 (0.4) |
0 |
1 (0.7) |
0.42
(0.01 - 10.41) |
0.52 |
1 (2) |
0 |
14.19 (0.56 - 353.74) |
0.10 |
Women with term delivery |
99 (91.0) |
49 (94.2) |
50 (87.7) |
0.28 (0.55 - 9.35) |
0.24 |
11 (6.1) |
70 (98.5) |
0.02 (0.002 - 0.23) |
0.001 |
No. of term delivery |
214 (77.0) |
100 (81.3) |
114 (73.5) |
1.56 (0.87 - 2.78) |
0.12 |
27 (55.1) |
187 (81.6) |
0.27 (0.14 - 0.53) |
0.0001 |
Women with preterm delivery |
17 (15.6) |
9 (17.3) |
8 (14.0) |
1.28 (0.45 - 3.61) |
0.63 |
8 (44.4) |
9 (12.6) |
5.51 (1.72 - 17.63) |
0.004 |
No. of preterm deliveries |
18 (6.5) |
9 (7.3) |
9 (5.8) |
1.28 (0.49 - 3.33) |
0.61 |
8 (16.3) |
10 (4.3) |
4.76 (1.73 - 13.08) |
0.002 |
Women with stillbirth |
5 (4.6) |
1 (1.9) |
4 (7.0) |
0.25 (0.02 - 2.31) |
0.22 |
2 (11.1) |
3 (4.2) |
0.96 (0.155 - 5.99) |
0.96 |
No. of stillbirths |
5 (1.8) |
1 (0.8) |
4 (2.5%) |
1.26
(0.07 - 20.38) |
0.86 |
2 (4.1) |
3 (1.3) |
3.20 (0.52 - 19.71) |
0.20 |
Unsuccessful pregnancy |
7 (2.5) |
2 (1.6) |
5 (3.2) |
0.41 (0.07 - 2.24) |
0.30 |
6 (12.2) |
1 (0.4) |
35.00 (3.86 - 317.08) |
0.001 |
Delivery mode |
|||||||||
Number of normal vaginal
delivery |
166 (60.0) |
73 (59.0) |
93 (60) |
0.97 (0.60 - 1.57) |
0.91 |
17 (34.6) |
149 (65.0) |
0.28 (0.15 - 0.54) |
0.0001 |
Number
of caesarian sections |
66
(24.0) |
34
(27.6) |
32
(21) |
1.46
(0.84 - 2.55) |
0.17 |
18
(36.7) |
48
(21.0) |
2.18
(1.12 - 4.24) |
0.02 |
Obstetrics
complications |
|||||||||
Gestational
hypertension |
1
(0.4) |
0 |
1
(0.7) |
0.42
(0.01 - 10.41) |
0.52 |
0 |
1
(0.4) |
1.53
(0.06 - 38.33) |
0.79 |
No.
of preeclampsia |
3
(1.1) |
2
(1.6) |
1
(0.7) |
2.54
(0.22 - 28.4) |
0.44 |
2
(4.1) |
1
(0.4) |
9.70
(0.81 - 109.2) |
0.06 |
Newborn
outcomes |
|||||||||
No.
of live births |
228
(82.0) |
107
(87.0) |
121
(78.0) |
2.17
(1.14 - 4.12) |
0.10 |
33 |
191 |
0.41
(0.20 - 0.81) |
0.01 |
Women
with very low birth weight infants (< 1500 g) |
4
(3.1) |
1
(1.9) |
3
(5.2) |
0.35
(0.03 - 3.50) |
0.37 |
2
(11.1) |
2
(2.81) |
4.31
(0.56 - 32.9) |
0.15 |
No.
of women with very low birth weight infants (< 1500 g) |
5
(1.7) |
1
(0.8%) |
4 (2.5%) |
0.31
(0.03 - 2.82) |
0.29 |
3
(6.1) |
2
(1) |
7.40
(1.20 - 45.55) |
0.03 |
Women
with neonatal death |
3
(2.7) |
1
(1.9) |
2
(3.5) |
0.53
(0.04 - 6.12) |
0.61 |
1
(5.5) |
2
(2.81) |
2.02
(0.17 - 23.71) |
0.57 |
No.
of neonatal death |
4
(1.4) |
1
(0.8) |
3
(1.9) |
0.41 (0.04 - 4.04) |
0.44 |
1
(2) |
3
(1.3) |
1.56
(0.15 - 15.41) |
0.69 |
¶dsSSc:
Diffuse Cutaneous Systemic Sclerosis; #No (%): Number (percentage); *lcSSc: Limited Cutaneous Systemic Sclerosis; £OR
(CI): Odds Ratio (confidence interval).