Between-group comparisons (NS vs. CS vs. HA) regarding the length of time to conversion to THR.

Table 10: Between-group comparisons (NS vs. CS vs. HA) regarding the length of time to conversion to THR.

X-ray pattern	Time (month) to conversion to THR	Comparisons: Treatment 1 vs. Treatment 2 Median (Months)		p-value^*
K/I III-‘A’	NS^# - M36	MMW-HA vs. NS	48 vs. 36	< 0.001
K/I III-‘A’	MMW-HA^# - M48	MMW-HA vs. NS	48 vs. 36	< 0.001
K/L-III’I’	NS^# - M48	MMW-HA vs. NS	60 vs. 48	< 0.001
	DM^# - M48	MMW-HA vs. DM	60 vs. 48	< 0.001
	MMW-HA^# - MM60	NS vs. DM	48 vs. 48	= 1
K/L-III’H’	NS^# - M60	MMW-HA vs. NS	72 vs. 60	< 0.001
	DM^# - M60	MMW-HA vs. DM	72 vs. 60	< 0.001
	MMW-HA^# - M72	NS vs. DM	60 vs. 60	= 1
K/L-II’A’	NS^# - M60	MMW-HA vs. NS	78 vs. 60	< 0.001
K/L-II’A’	MMW-HA^# - M78	MMW-HA vs. NS	78 vs. 60	< 0.001
K/L-II’I’	NS^# - M72	MMW-HA vs. NS	96 vs. 72	< 0.001
	DM^# - M72	MMW-HA vs. DM	96 vs. 72	< 0.001
	MMW-HA^# - M96	NS vs. DM	72 vs. 72	= 1
K/L-II’H’	NS^# - M84	DM vs. NS	84 vs. 84	= 1
K/L-II’H’	DM^# - M84	DM vs. NS	84 vs. 84	= 1

NS - control group; MMW-HA - Euflexxa group; DM - Depo Medrol (CS group); ^# -Each study group included 25 subjects; K/L -I/ II/ III - radiographic grades according to Kellgren-Lawrence; ‘A’ / ’I’ / ’H’ - radiographic patterns (atrophic/intermediate/hypertrophic); ^*-Mann-Wythney (comparisons between ‘A’-patterns)/Kruskal-Wallis (comparisons between ‘H’ and ‘I’-patterns) tests with Dunn-Bonferroni post hoc analysis.