Table 1: Neurological symptoms: Unilateral involvement of the cranial nerves of the cerebellopontine angle.
N. Cases | Authors/Year | Age/Sex | Origin | Duration of Symptoms | Symptoms | Surgical Treatments | Histology | Adjuvant Treatments | Outcome |
1 | Swaroop and Whittle [2] | 22 M | Pons | 1 Year | Hearing Loss, Ataxia, Dysphagia | Subtotal Resection | GBM IV | ---- | ---- |
2 | Kasliwal, et al. [3] | 11 M | Cerebellum | 15 Days | VII and VIII CN Dysfunction | Subtotal Resection | GBM IV | ---- | Dead after 2 Months |
3 | Rasalingam, et al. [4] | 9 M | Pons | 2 Weeks | ICH, Ataxia, Fever | Subtotal Resection | GBM IV | None | Dead after 2 Months |
4 | Wu, et al. [5] | 60 M | CN VIII | 2 Months | Hearing Loss, Facial Pain, Dysarthria, Dysphagia | Subtotal Resection | GBM IV | None | Dead after 2 Months |
5 | Salunke, et al. [6] | 59 M | Pons | 3 Months | Hearing Loss, Ataxia, Hemiparesis, ICH | Subtotal Resection | GBM IV | RT | ---- |
6 | Matsuda, et al. [7] | 69 M | Cerebellum | 1 Hour | r. Facial Pain | Subtotal Resection | GBM IDH neg, Ki67 23% | RT + TMZ (Stupp Protocol) | Alive at 24 Months |
7 | Lee, et al. [8] | 71 F | ? | 3 Months | Ataxia, Memory Loss | Stereotactic Biopsy | GBM IV Ki67 Li: 30% | RT + TMZ (Stupp protocol) | Alive at 1 Year |
8 | Panigrahi, et al. [9] | 52 F | Cerebellum | 2 Months | ICH, Ataxia | Near Total Resection | GBM IV | RT | Alive at 3 Months |
9 | Takami, et al. [10] | 55 M | CN VIII | ---- | Hearing Loss, Ataxia, Facial Paresis | Subtotal Resection | GBM IV | ---- | ---- |
10 | Yang, et al. [11] | 55 M | CN VIII | 3 Months | r. Deafness and Facial Palsy, Ataxia, ICH | Subtotal Resection | GBM IV Ki67 Li: 70% | None | Dead at 2,5 Months |
11 | Present Report | 49 F | Cerebellum | 2 Weeks | l. Deafness, Trigeminal Pain, Ataxia | Subtotal Resection | GBM IV Ki67 Li: 30% | RT+TMZ (Stupp Protocol) | Cervical Cord Metastasis. Dead after 15 Months |
CN: Cranial nerve; ICH: Intracranial hypertension; GBM: Glioblastoma; RT: Radiotherapy; TMZ: Temozolomide.