Table 1: Clinical summary of known cases of primary intramedullary brainstem & spinal cord astroblastoma with EWSR1/BEND2 fusion.

Source

Age

Sex

Location

Surgery

Chemotherapy

Radiotherapy

Outcome

Current Study

45

F

Cervical

Total resection

Referred

Referred

Alive, independent with neurological deficit.

Lucas, et al. [4]

6

F

Cervical

Biopsy

No

No

Died at 25 months, disease progression at 12 months.

Lucas, et al. [4]

20

M

Brainstem

Biopsy

Unknown

Unknown

Unknown

Smith-Cohn, et al. [10]

38

M

Cervico-medullary

Subtotal resection

Temozolomide

50.4 Gy/28 Fr

Alive, independent with pain controlled by oral analgesia.

Tsutsui, et al. [12]

36

M

Thoracic

Partial debulking

Bevacimumab & Temozolomide

54 Gy/30 Fr

Alive, disease progression & distant dissemination at 12 months.

Yamasaki, et al. [11]

3 mo

M

Cervico-medullary

Partial debulking

Temozolomide, Etoposide & Bevacimumab

No

Died at 1 month.