Table 2: Summary of recommended diagnostic tools, drugs and treatment procedure for phaeochromocytoma in pregnancy [3,5,11,15,27-30,33-35,37-40].

Diagnostic Tools	Drugs	Treatment Procedure
Biochemical investigations (all trimesters and postnatal period): Plasma free metanephrines or 24 hour urine fractionated metanephrines Imaging: 1^st trimester Abdominal ultrasound (1^st trimester) MRI without gadolinium 2^nd and 3^rd trimester MRI without gadolinium Postnatal period CT MIBG Iodine	Pre-operative control of catecholamine excess: α-adrenergic antagonist Phenoxybenzamine Prazocin Doxazocin β-receptor antagonist Esmolol Labetolol Propanolol Metoprolol Atenolol Bisoprolol Short-acting calcium channel blockers Nicardipine Clevidipine Management of acute catecholamine excess: The above ± the following can be considered Magnesium Sulphate Other direct vasodilators Hydralazine Nitroglycerin Sodium Nitroprusside	Factors to be considered: Location of tumour Gestation age of pregnancy Adequacy of blood pressure control Multiple or malignant tumours Accessibility of the lesion to surgery Treatment Procedure: 1^st trimester Surgery is associated with a higher incidence of miscarriage and only recommended for life-threatening situation unresponsive to medical treatments. 2^nd trimester Surgical resection of the tumour (adrenalectomy). Laparoscopic approach is the treatment of choice. 3^rd trimester Delivery is planned with concurrent or delayed adrenalectomy

Abbreviations

CT: Computed Tomography; MIBG: Metaiodobenzylguanidine; MRI: Magnetic Resonance Imaging.