Table 6: Factors weighing in on the selection process of patients for MRgFUS procedure.

Factors Treatment might be helpful without complications No treatment necessary/Treatment possibly harmful Possible countermeasures to negative factors Relative numbers [116,120]
Symptoms relevance Significant symptoms No significant symptoms Preventive treatment -
Fibroid type Any non-pedunculated Pedunculated Release of fibroid into abdominal cavity never documented 5/373 (1.34%)
Overall: 1-5%
Fibroid size 3-10 cm < 3 cm; > 10 cm/> 300 ml Multiple treatments, GnRHa 20/373 (5.36%)
Overall: 5-11%
Distance from skin Inside available treatment area > 50% outside of possible treatment area Thin gel pad; rectal filling 2/373 (0.53%)
Fibroid number ≤ 6 > 6 fibroids - 45/373 (12.06%)
Distance from Bones - Close to vertebrae or sacrum Tilting beam path; rectal filling; multiple, smaller treatments -
Obstacles along US beam path None Scars, bone, air, bowel Rectal/bladder fill, beam angulation 2/169 (1.18%)
Fibroid vascularity Little vascularity Increased vascularity GnRHa -
Beam aberration - Tissue irregularities along the beam path - -
Adenomyosis - Presence of adenomyosis Possibly treatment 16/373 (4.29%)
Malignancy - Presence of malignancy Surgical intervention 19/373 (4.29%)

GnRHa: Gonadotropin Releasing Hormone analog; US: Ultrasound.