Table 2: Study results.

Article

Time of diagnose

Symptoms

Investigations

Given treatment

Maternal outcome

Delivery

Fetal outcome

Pathogens identified in mother

Follow-up

Pollak, et al.

[13]

1st trimester

Bilateral leg weakness

Laboratory test

5 doses of IVIG

Complete recovery

Spontaneous vaginal at 40 weeks

Neonatal CMV infection

n/a

2 years

JE Mendizabal, et al.

[12]

10th week

Paraesthesia, Progressive symmetrical weakness in legs, Facial paresis, Difficulty swallowing

CSF;

Serological testing of infectious diseases;

EMG

5 days of IVIG;

Monitoring at ICU

 

Requiring outpatient rehabilitation

Vaginal at 25th week

Fetal death at 25th week of gestation, Congenital CMV infection

CMV

n/a

Kokubun, et al. [11]

6th week

Paraesthesia, Weakness in arms and legs, Absent tendon reflexes

Serological testing positive for IgG anti-GM1 and -GD1b antibodies;

Declined CSF examination, EMG

Declined IVIG treatment

Complete recovery after 25 days

Miscarriage at 8th week of gestation

Miscarriage

n/a

3 months

Brooks, et al. [10]

7th week

Progressive weakness in total body, Respiratory insufficiency

n/a

IVIG and plasmapheresis; Mechanical ventilation

Full recovery (after 9 months of total hospitalization)

C-section at 38th week gestation due to genital warts

Healthy

n/a

n/a

N/a: Not available; CMV: Cytomegalovirus; CSF: Cerebrospinal fluid; ICU: Intensive care unit; EMG: Electromyography