Table 2: Study results.
Article |
Time of diagnose |
Symptoms |
Investigations |
Given treatment |
Maternal outcome |
Delivery |
Fetal outcome |
Pathogens identified in mother |
Follow-up |
Pollak, et al. [13] |
1st trimester |
Bilateral leg weakness |
Laboratory test |
5 doses of IVIG |
Complete recovery |
Spontaneous vaginal at 40 weeks |
Neonatal CMV infection |
n/a |
2 years |
JE Mendizabal, et al. [12] |
10th week |
Paraesthesia, Progressive symmetrical weakness in legs, Facial paresis, Difficulty swallowing |
CSF; Serological testing of infectious diseases; EMG |
5 days of IVIG; Monitoring at ICU
|
Requiring outpatient rehabilitation |
Vaginal at 25th week |
Fetal death at 25th week of gestation, Congenital CMV infection |
CMV |
n/a |
Kokubun, et al. [11] |
6th week |
Paraesthesia, Weakness in arms and legs, Absent tendon reflexes |
Serological testing positive for IgG anti-GM1 and -GD1b antibodies; Declined CSF examination, EMG |
Declined IVIG treatment |
Complete recovery after 25 days |
Miscarriage at 8th week of gestation |
Miscarriage |
n/a |
3 months |
Brooks, et al. [10] |
7th week |
Progressive weakness in total body, Respiratory insufficiency |
n/a |
IVIG and plasmapheresis; Mechanical ventilation |
Full recovery (after 9 months of total hospitalization) |
C-section at 38th week gestation due to genital warts |
Healthy |
n/a |
n/a |
N/a: Not available; CMV: Cytomegalovirus; CSF: Cerebrospinal fluid; ICU: Intensive care unit; EMG: Electromyography