Table 1: Details of intramural pregnancies identified in January 2015-November 2020.
Authors |
Years |
Gestational age |
History of gynecology and Obstetrics |
Manifestations |
Imaging features |
Management |
Wang, et al. |
2015 |
21 |
G3P1A1; D&C (×2) (second for intrauterine residues) |
Vaginal bleeding |
Ultrasound and MRI showed an empty endometrial cavity and a GS with a fetus implanted in the right posterior lateral side of the uterus fundus |
Laparotomy with resection under temporary balloon occlusion of abdominal aorta |
Nees, et al. |
2015 |
32 |
D&C (×1) |
Vaginal bleeding |
- |
Laparotomy with hysterectomy |
Li, et al. [14] |
2016 |
20 |
G1P0 |
- |
A 14 × 14 cm GS on the right posterior lateral side of the uterus fundus |
Laparotomy with resection under temporary balloon occlusion of transfemoral aorta |
Bechev, et al. [11] |
2017 |
28 |
G1P0; LSCS (×1); Salpingectomy of the left tube, Isthmic obstruction of the right tube; IVF-ET |
- |
A GS with presence of yolk sac measuring 1.2 cm were scanned in the posterior wall of the uterus, Completely surrounded by myometrium |
US-guided MTX injected in the GS |
Kong, et al. [10] |
2017 |
20 |
G1P0; D&C (×1) |
- |
The GS at a distance from the cavity, With a compressed myometrium between the two of them; MRI showed the GS was embedded into the myometrium in the right posterior wall of the uterine |
Laparotomy with resection under UAE |
Mahmoud, et al. [1] |
2017 |
33 |
G8P7; CS (×1) |
Vaginal bleeding and Abdominal pain, Nausea and Vomiting |
An empty uterine cavity and a 28 mm, Well- defined GS located in the anterior myometrium of the lower uterine segment |
Laparotomy with resection |
Mahmoud, et al. [1] |
2017 |
34 |
G2P1; |
- |
Ultrasound and MRI indicated a mixed echogenic mass measuring 5.1 × 4.6 cm located within the posterior wall of the uterine fundus with an abundant blood supply |
Hysteroscopy and laparotomy with resection following MTX-based chemotherapy |
Liu, et al. [10] |
2017 |
34 |
G2P1; D&C (×1); Laparoscopic surgery for endometriosis
|
- |
A heterogeneous mass measuring 3.7 × 3.3 cm in the posterior wall, Extending to the uterineserous layer; MRI indicated an irregular signal area in the left wall within the myometrium of the uterus |
Hysteroscopy and Laparoscopic resection |
|
|
19 |
G1P0; D&C (×1) |
Vaginal bleeding and Vomiting |
A heterogeneous mass measuring 4.2 × 2.9 cm in the left posterior wall of the uterus
|
Laparoscopic resection |
|
|
40 |
G4P0 |
Severe abdominal pain |
A heterogeneous echogenic mass (5.4 × 4.4 cm) in the right side of the uterine wall, close to the corneal tissue, and the embryo bud not connected with the endometria |
Hysteroscopy and Laparoscopic resection |
Lyu, et al. [7] |
2018 |
26 |
G2P0; Right salpingectomy; IVF-ET (twin pregnancy) |
- |
Intrauterine pregnancy with another mass measuring 2.0 × 2.0 cm in the left cornua separate from uterine cavity and surrounded by musculature |
Laparoscopic resection (another led to a live birth) |
Vagg, et al. [2] |
2018 |
34 |
G2P2; Open Myomectomy (×1) |
- |
A GS measuring 8.0 × 7.9 × 7.0 cm within the myometrium of the right uterine cornua |
Laparotomy, Hysterectomy and Bilateral salpingectomy |
Yang, et al. [13] |
2019 |
31 |
- |
- |
A GS measuring 3.0 × 2.0 × 1.1 cm in the righthorn of the uterus surrounded by the myometrium |
Hysteroscopy and Laparoscopic resection with injection of terlipressin (6U) |
You, et al. [9] |
2019 |
35 |
G5P3; IUD (×1); Adenomyosis |
Severe pelvic pain and Hypotension |
A mass (7.0 × 5.0 cm) was located in the uterus |
Laparoscopic resection |
Zhang, et al. [3] |
2019 |
30 |
G1P1; CS (×1) |
Vaginal bleeding |
A mass measuring 4.0 × 3.0 × 3.0 cm was observed in the posterior wall below the left horn of the uterus |
Laparoscopic resection with injection of terlipressin (6U) and MTX (50 mg) |
Chaikof, et al. [8] |
2020 |
35 |
G2P2; D&C (×1); Asherman syndrome |
- |
The GS was located within 3 mm of the uterine serosa |
Local resection |
Liu, et al. [5] |
2020 |
28 |
G2P1; Right salpingectomy; IVF-ET |
- |
A ill-defined hypoechogenic structure with 14 × 13 mm in size was between the right ovary and the uterus contour |
Hysteroscopy and Laparoscopic resection |
Nees, et al. [4] |
2020 |
24 |
CS (×1) |
- |
A 4.3 × 3.5 cm mass containing a GS with a viable embryo was seen on the left side of the uterus |
Laparotomy with uterine wedge resection |
This report |
2020 |
33 |
G4P1; D&C (×1) |
Vaginal bleeding, Slight chest tightness and Nausea |
A mass measuring 38 × 43 × 40 mm with uneven echo located in the right lateral wall of uterus |
Chemotherapy of EMA-CO, Hysteroscopy and Laparotomy with resection |
D&C: Dilatation and Curettage; GS: Gestational Sac; LSCS: Laparoscopic Hysteromyomectomy; MTX: Methotrexate; IVF-ET: In Vitro Fertilization and Embryo Transfer; UAE: Uterine Artery Embolization; IUD: Intrauterine Contraceptive Device; CS: Cesarean Section