Histopathological and Biochemical Response of Chrysichthys Nigrodigitatus to Environmental Stressors from Two PollutedLagoons, Southwest Nigeria
Bassey Okon Bassey
Article Type: Research Article | First Published: June 17, 2019
Stressful environmental conditions are ecological force in modulating adaptive responses of fish populations in aquatic ecosystems with a large number of biochemical and physiological effects associated with increased fluxes of oxyradicals. This study was aimed to examine the impacts of oxidative stress and histological changes in organs of Chrysichthys nigrodigitatus from Ologe and Badagry lagoons. Biomarkers such as biochemical markers [malondialdehyde (MDA) and superoxide dismutase (SOD) and catalase (CAT) and glutathione (GSH)] and histological marker were analysed in C. nigrodigitatus usi...
Effects of Fumes Inhaled from Cooked Meat
Shivam Joshi, MD
Article Type: Review Article | First Published: June 14, 2019
Since 2015, the World Health Organization has regarded the ingestion of processed meat as a definite carcinogen and red meat as a probable carcinogen, basing their recommendations on studies showing an increased risk of colorectal cancer. The findings have led many to limit their ingestion of red and processed meat. Over the past several decades, a growing body of literature has formed regarding the possible harmful, if not carcinogenic, effects of fumes emanating from cooked meat on humans. In this article, we discuss the evidence available on the subject....
Current Metal Pollution Status and Ecological Risk Impacts on Ologe and Badagry Lagoons In Lagos, Nigeria
Bassey O Bassey, Chibuisi G Alimba and Obinna L Chukwu
Article Type: Original Article | First Published: June 15, 2019
Contamination of aquatic environment is increasing and has been associated with indiscriminate discharge of solid wastes and effluents generated from industrial, domestic and agricultural activities. These wastes and effluents contain harmful substances, such as metals, which constitute a major problem on the quality of the Nigerian coastal water. This study evaluated the impacts of heavy metals on the water and sediment quality of Ologe and Badagry Lagoons, South-West Nigeria. The heavy metals (Cr, Cd, Cu, Zn, Pb and Fe) in water and sediments was analyzed with atomic absorption spectrophotom...
Observations on Restless Legs Syndrome and Indications of the Cause
Melrose Truett Garrett, Jr. Sc.D
Article Type: Short Note | First Published: June 24, 2019
RLS accompanying loose stool (not diarrhea) indicated two hypotheses: 1) Medications for diarrhea will relieve RLS, 2) RLS is caused by pressure in the colon blocking a femoral vein, the nervous system then causes muscle contraction in the leg. In tests both were sustained. Soluble fiber corrects loose bowels but the number of Americans with insufficient fiber is much greater than those with RLS....
Diet and Microbiome Influence on Alopecia Areata: Experience from Case Reports
Rinaldi Fabio, MD, Pinto Daniela, Giammaria Giuliani and Sorbellini Elisabetta
Article Type: Case Report | First Published: July 22, 2019
Alopecia areata (AA) is a potentially reversible auto-immune non-scarring baldness on the scalp, which can be extended to the entire body. There are many scientific evidence as regards the impact of diet on scalp diseases related to hair growth. Diet is also able to strongly influence gut microbiome. On the contrary, few evidence reports as regards the link between microbiome, especially scalp microbiome and hair diseases. Here we reported a two case-reports study on patients affected by AA, with and without lactose intolerance, respectively, with the aim to underline how diet could emphasize ...
Does Preoperative Carbohydrate Loading Help Outcomes in Total Knee Replacement Surgery?
Radha Reddy Chada, PhD, RD, Venkateshwar Reddy Maryada, MBBS, MS, CHS, Praharsha Mulpur, MBBS, DNB, Annapareddy V Gurava Reddy, MBBS, DNB, FRCS (Ed), FRCS, FRCS, M.Ch, Anita Maska and Veena Diggikar, PhD
Article Type: Original Article | First Published: June 22, 2019
Prolonged overnight fasting prior to surgery was advocated to reduce the risk of aspiration during or after surgery. Recent studies suggest prolonged fasting is associated with increased insulin resistance, increased acute phase stress response and decreased well-being among surgical patients. Our hypothesis is that pre-operative oral carbohydrate loading 2 hours prior to surgery is associated with improved patient reported well-being....
Frequency and Characterization Meningococcal Carriage Isolates, among Prisoner's Inmates from Mexico City
Luz Elena Espinosa de los Monteros Perez, Jimsenez Rojas LV, Gomez-Barreto D and Vazquez Moreno JA
Article Type: Research Article | First Published: June 27, 2019
Meningococcal disease in Mexico has a very low incidence; it is one of the countries with few reported cases as prevalence of the carrier state is unknown. Some studies have shown that many invasive meningococcal diseases are restricted to a specific number of hyper-virulent strains that contrast with carrier isolates. The aim of this study was to determine the frequency and characterization of meningococcal carriage isolates among prisoner's inmates. Nasopharyngeal swabs were obtained, Neisseria meningitidis was identified by standard methods, Polymerase Chain Reaction, and penicillin suscept...
Epidemiological Notes about Bartonellosis Reactive Samples in Brazil
Maria de Fatima Goncalves Lopez Silva, Francisco Alexsandro Sousa Mesquita, Bidiah Mariano da Costa Neves and Stefan Vilges de Oliveira
Article Type: Short Communication | First Published: June 21, 2019
artonellosis or Cat Scratch Disease (CSD) is defined as an infectious, benign illness that in most cases results from the scratching, licking or biting of animals carrying the bacterium Bartonella henselae. This study aims at describing the epidemiological profile of serologically reactive samples between the years 2011 and December 2017 in Brazil. Official data from the requests for diagnostic tests registered in GAL (Gerenciador de Ambiente Laboratorial/Laboratory Environment Manager) in the Ministry of Health of Brazil were analyzed. The reactive samples were selected by their place of occu...
SVMOneClAS: Pipeline for Efficient Splicing Events Calling
Sokolov A, Mazur A, Zhigalova N, Prokhortchouk A, Gruzdeva N and Prokhortchouk E
Article Type: Research Article | First Published: June 05, 2019
Splicing is a part of mRNA maturation process when exons of pre-mRNA transcript are joined in multiple ways. In case of alternative splicing, some exons may be excluded from the final mRNA, and the resulting ensemble of mRNAs creates different protein isoforms, allowing multiple proteins to be coded by a single gene. To detect new events of alternative splicing in human blood cells, we used RNA-seq technology. A pipeline based on Python "Scikit-Learn" library was developed for efficient splicing events calling. We found 8728 potential candidates, 20 of which were selected for RT-PCR and 8 were...