Risk of Osteonecrosis of the Jaw in Patients with Postmenopausal Osteoporosis: A Systematic Literature Review
Gloria Candelas, Virginia Villaverde, Petra Diaz, Mercedes Guerra and Antonio Naranjo
Article Type: SYSTEMATIC REVIEW | First Published: July 25, 2019
The studies retrieved by the above strategies were included if they met the following pre-established criteria. The patients studied had to be diagnosed of osteoporosis (all ages, both sexes), and they had to be taking Dmab. We measured the likelihood of having osteonecrosis of the jaw. We included in the search for systematic reviews randomised clinical trials (RCT) and cohort studies. We excluded articles on cancer or other disease other than osteoporosis, animal and basic science studies....
A Review of the Most Common Dermatologic Conditions and their Debilitating Psychosocial Impacts
Madeeha Mian, BA, Annika S Silfvast-Kaiser, MD, So Yeon Paek, MD, Dario Kivelevitch, MD and Alan Menter, MD
Article Type: Review Article | First Published: July 22, 2019
The majority of skin conditions are not life-threatening; however, many can be severe and disfiguring enough to devastate a patient's quality of life. Skin diseases can significantly impact not only a patient's physical appearance, but also their social and emotional well-being. Even the smallest skin lesions have been shown to disrupt a person's level of overall wellness. Here, we aim to address the potential psychological and emotional impact of the most common and debilitating dermatologic conditions. We describe how skin disorders affect individuals and subsequently, how they are perceived...
Acute Intratumoral Hemorrhage of a Brain Glioma during Pregnancy: Case Report and Considerations on the Management Strategy
Andrea Bianco, Riccardo Fornaro, Christian Cossandi, Sara Forgnone, Emanuela Crobeddu and Piergiorgio Car and Gabriele Panzarasa
Article Type: Commentary | First Published: July 05, 2019
Pregnancy can change the behavior of brain gliomas with increased growth rate, increased frequency of seizures, and anaplastic transformation. Very rarely the presentation may be hyperacute due to intratumoral hemorrhage. We report and discuss them a management of the hemorrhagic infarction of a newly diagnosed postcentral anaplastic astrocytoma in a pregnant woman. A first MRI discovered the glioma; two days later, after acute neurological deterioration, a second MRI showed a dramatic increase in volume with intratumoral hemorrhage, possibly caused by venous thrombosis....
Prevalence of Anemia and Associated Factors among Children Attended at Jimma Medical Center, South West Ethiopia
Bikila Dereje Fufa, BSc, MSc and Habtamu Gutema, BSc
Article Type: Research Article | First Published: July 15, 2019
Anemia is major health problem throughout the world. It is associated with serious consequences including growth retardation, impaired motor and cognitive development, and increased morbidity and mortality. Estimates suggest that 47.4% of children are anemic globally. The magnitude of the problem in developing countries is high, since they are more exposed to various health and socioeconomic problems which are directly or indirectly related with anemia....
Epileptiform Activity in Patient with RBD-Like Symptomatology
Isabel Loucao Amorim, MD, Linda Azevedo Kauppila, MD, Mariana Reis Costa, MD, Carla Bentes, MD, PhD, and Rita Peralta, MD
Article Type: Case Report | First Published: July 06, 2019
REM sleep behavior disorder shares some clinical similarities with nocturnal epileptic seizures, which can result in misdiagnosis. We report a case of a man with Parkinson Disease diagnosis and parietal and frontal meningiomas who started to have abnormal sleep behaviors, suggestive of REM sleep behavior disorder. Video-polysomnographic showed periodic bilateral occipital epileptiform activity that occurred near arousals, where subtle movements were detected. During REM sleep no loss of atonia nor abnormal behaviors were detected. He was started on antiepileptic drugs, with improvement of the ...
ANA-Hep2 Positive with Anti-Rods and Rings Pattern in a Child without Hepatitis C under Treatment: Case Report
Mariana Magerl, Rinaldo Ferreira Gandra and Rafael Andrade Menolli
Article Type: Case Report | First Published: July 11, 2019
The immunofluorescence pattern of antinuclear antibodies (ANA) called rings and rods (RR) has only recently been described. This pattern has been associated with patients with Hepatitis C at treatment. There are few studies that demonstrate their appearance in healthy individuals or with other health conditions. This study reports positivity of this autoantibody in a patient never exposed to the HCV virus, in order to understand its clinical significance....
Dietary Habits of Women with Rheumatoid Arthritis Differ from that of Women without the Disease: Results from a Population-Based Study
Klara Nypelius Standley, Inger Gjertsson, Anna Winkvist and Helen M Lindqvist
Article Type: Research Article | First Published: July 04, 2019
Nutritional status of patients with rheumatoid arthritis (RA) is often poor. In addition, popular trends in avoiding certain foods have been noted among patients with RA yet recent data on dietary intake is lacking. The aim of the present study was to examine possible differences in food intake between Swedish women with and without RA. In total 150 women with RA, selected from the Swedish Rheumatology Quality Register, and 163 women without RA, answered a postal food frequency questionnaire includsing questions on 45 food items, food choices, age, weight, height, educational level and serious...
Tuberculous Spondylodiscitis in a Military Hospital in Gabon: Report of Eleven Patients
Mangouka Guingali Laurette, Iroungou Berthe A, Bivigou-Mboumba Berthold, Oura Landry, Mwanyombet Lucien and Nzenze Jean Raymond
Article Type: Research Article | First Published: July 04, 2019
Extrapulmonary forms of tuberculosis (TB) are on the rise in sub-Saharan Africa and pose a major public health problem. The spine is the most frequent location of musculoskeletal tuberculosis. Involvement of the spine causes severe back pain and weakness in the lower extremities. We report 11 cases of TB spondylodiscitis, commonly referred to as Pott's disease, who presented to the internal medicine department at the Military Hospital of Gabon (HIA OBO)....
New Pharmacologic Therapy for Hypertension in Pregnancy
Article Type: Review Article | First Published: July 03, 2019
There has been virtually no change for three decades in the treatment of hypertension in pregnancy and it's many namesakes: Pre-eclampsia, gestational hypertension, superimposed preeclampsia, gestosis, etc. all of which shall be referred to in the rest of this article as PIH. In part this is because of an incomplete understanding of its physiology and pathophysiology, partly because the only widely accepted treatment, labetalol, does not work well and causes fetal growth restriction. This is a short review of what we know about PIH and normal placental physiology, what we surmise about the dis...
Critical Challenges of Economic and Social Issues in Secondary Prevention of Cardiovascular Disease
Rubina Barolia, Gina Higginbottom, Wendy Duggleby and Alexander M Clark
Article Type: Original Research | First Published: July 06, 2019
What we eat may cause Cardiovascular Disease (CVD), and a healthy diet is a key factor in the prevention of CVD. Promoting healthy diet is challenging, particularly for people with low Socioeconomic Status (SES), because poverty is linked with many risk behaviours such as smoking, unhealthy eating, and obesity. Multiple factors make healthy eating very challenging. Underpinned by critical realism, this study explores the factors that inform Pakistani people of low socio-economic status SES in making decisions on food choices after diagnosis with CVD....