ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2378-3516/1410125

Association between Cigarette Smoking and Serum Gamma-Glutamyl Transferase Level

Dongcheol Lee, Hyun Wuk Kang and Yu Il Kim

Article Type: Research Article | First Published: Lee D, Kang HW, Il Kim Y (2019) Association betwee

Gamma-glutamyltransferase (GGT) is an enzyme mainly produced from the cells of the hepatobiliary tract. And, it has been introduced as a biomarker for oxidative stress mainly by alcohol consumption and current smoking. This study was performed to evaluate the association between smoking status and serum GGT concentration. The effect of cigarette smoking on serum activities of the enzyme, GGT was investigated using the data of the 5th Korea National Health and Nutrition Examination Survey (5th KNHANES, 2010 to 2012); a cross sectional survey in the general population of Korea....

 Open Access DOI:10.23937/2378-3001/1410093

Investigating the Effects of Phenytoin, Phenobarbital, Topiramate, Carbamazepine and Sodium Valproate on the Neurotransmitter Speed in Treated Seizure Children

Farzad Ahmadabadif, Ghasem Fattahzadeh, Abolfazl Atalu and Pooya Badihi

Article Type: Research Article | First Published: December 18, 2019

Anticonvulsants such as phenytoin, phenobarbital, topiramate, carbamazepine and valproate due to their beneficial effects and economic benefits in compare to new drugs are used more but these drugs are not harmless and sometimes had dangerous, safe and reversible side effects. Reduction of the nervous conduction velocity (NCV) is the common side effect of these drugs and it is of clinically importance if it is severe especially in treated children. Therefore, it is necessary to evaluate and compare the effect of each drug on NCV. The aim of this study was to investigate the effects of antiepil...

 Open Access DOI:10.23937/2643-3885/1710038

Foot Care Education, Health-Seeking Behaviour and Disease Outcome in Patients with Diabetic Foot Ulcer: Results from the Multi-Centre Evaluation of Diabetic Foot Ulcer in Nigeria Study

Innocent Okpe, Ejiofor Ugwu, Olufunmilayo Adeleye, Ibrahim Gezawa, Marcelina Enamino and Ignatius Ezeani

Article Type: Research article | First Published: December 16, 2019

Considerable advances have been made in the field of diabetic foot care over the past 25 years in developed countries. On the contrary, diabetes foot ulceration (DFU) still remains a common diabetes related complication of substantial public health importance in sub-Saharan Africa. Diabetic foot outcome in Nigeria is reportedly poor, with high amputation and mortality rates. Proper foot care education is known to impact positively on both DFU prevention and outcome in the developed societies. However, this relationship has not been well characterised in Nigeria....

 Open Access DOI:10.23937/2377-3634/1410115

Prevalence of Diabetes Mellitus in Outpatients with Essential Hypertension in a Rural Tertiary Hospital

Ogunmola Olarinde Jeffrey, Ajani Gbadebo Oladimeji and Olabinri Eunice Oluremi

Article Type: Original Article | First Published: December 16, 2019

To determine the prevalence of diabetes mellitus (DM) in patients with essential hypertension attending outpatient medical clinic in a rural community setting of a developing country. This cross-sectional study included patients of a medical outpatient clinic in Federal Teaching Hospital Ido Ekiti, Ekiti State, Nigeria. Study patients were consecutively recruited from Cardiac clinic and baseline investigations obtained from the patients’ files were evaluated including Fasting Blood Glucose (FBG).The estimated minimum sample size was 80 with probability of type 1 error, assumption of α = 0.0...

 Open Access DOI:10.23937/2469-5831/1510023

A Signal Detection Analysis of World Health Organization’s Pharmacovigilance Database

Yeqian Liu

Article Type: Original Article | First Published: December 14, 2019

Pharmacovigilance is the primary method used to identify hazards associated with medicinal products. Using generalized likelihood ratio tests, we examed the adverse reaction signals of the drug class Monoamine oxidase inhibitors (MAOIs) from World Health Organization’s Pharmacovigilance Database. The proposed test procedure has the ability of detecting adverse reactions of multiple drugs simultaneously. Our findings sugggest there are 23 common Adverse reaction signals detected within this drug class. And postural hypotension, high blood pressure, fainting, abnormal heart rhythm, dizziness, ...

 Open Access DOI:10.23937/2469-5696/1410046

First Observation of Two TMPRSS6 Gene Mutations (G603R and K636AFSX17) in Turkish Population

Yasemin Ardicoglu Akisin, Gulnaz Kurt, Hüseyin Onay, Ferda Ozkinay and Nejat Akar

Article Type: Case Report | First Published: December 20, 2019

Iron is one of the elements that participate numerous reaction on the body and the structure of hemoglobin to the purpose of carrying oxygen to the tissues. Thus, iron deficiency causes different problems in the body. Iron-refractory iron deficiency anemia (IRIDA) is a genetic disorder that has some signs of iron deficiency anemia (IDA) but refractory to oral iron and partially refractory to intravenous iron. The mutation in TMPRSS6 gene causes matriptase-2 protein deficiency that negatively regulates hepcidin molecule. Thus, increasing hepcidin connects its receptor ferroportin and decreases ...

 Open Access DOI:10.23937/2377-4630/1410100

Perioperative Management of Multiple Intracranial Nail Gun Injuries

Matthew B Ellison, MD, Jeremy Hensley, MD, Roy E Henrickson, MD, Jeffrey Puette, MD, Jason Shepherd, MD, Daniel Sloyer, MD and Pavithra R Ellison, MD

Article Type: Case Rep ort | First Published: January 04, 2020

A 51-year-old male presented to the emergency department with four self-inflicted nail gun wounds. Computed tomography angiography demonstrated three nails penetrating the frontal bone toward the falx cerebri causing small subdural hematomas. The fourth nail penetrated the parietal bone posteriorly, ending very close to the vein of Galen. Despite the ominous-appearing imaging, the patient was neurologically intact and cooperative to the point that consideration was given to the possibility of removal of the nails under local anesthesia. Due to the number of nails and proximity of the fourth na...

 Open Access DOI:10.23937/2377-4630/1410099

Does Esmolol Havean Effect on Erythrocyte Deformability in Rat Lower Limb Ischemia Reperfusion Injury?

Ali Dogan Dursun, Faruk Metin Comu, Aysegul Kucuk, Ulku Sabuncu, Nevriye Salman, Timucin Sabuncu, Gulay Kip, Omer Kurtipek and Mustafa Arslan

Article Type: Original Article | First Published: December 20, 2019

Ischemia reperfusion (I/R) injury is a common problem in vascular surgery. We aimed to investigate the effects of esmolol on erythrocyte deformability in rat lower limb I/R injury. Following Ethics Commitee approval 24 rats were randomly divided into 4 groups, Control (Group C), Esmolol (Group E), Ischemia-reperfusion (Group I/R), I/R-Esmolol (Group I/R-E). In I/R group, atraumatic microvascular clamp was placed to infrarenal abdominal aorta. After 120 minutes from ischemia, the clamp was removed and reperfusion was performed for 120 minutes. Esmolol (200 μg/kg/min) was administered 30 minute...

 Open Access DOI:10.23937/2469-5742/1510068

Letter to Editor: Lower Urinary Tract Mesh Perforations Following the Insertion of Mid-urethral Tapes or Transvaginal Mesh: A Tertiary Unit's Experience - Saidan, et al. 2019

Wael Agur

Article Type: Letter to Editor | First Published: December 25, 2019

It appears all women who had urinary tract perforation following mesh tape in the study underwent partial (rather than total) removal surgery, including the 8 women whose devices had been in place for less than 8 weeks. It is relatively easy to totally remove a device that had been recently implanted, before scar tissue is matured and removal becomes difficult. It is not clear whether separate groin incisions were employed during surgery to achieve total removal of the women’s trans obturator mesh devices....

 Open Access DOI:10.23937/2469-5742/1510067

Effect, Adverse Events and Re-operations after Tension-free Vaginal Tape Obturator Surgery

Silja Maigaard Axelsen, Rikke Guldberg Sorensen, MD, PhD and Susanne Axelsen, MD, PhD

Article Type: Original Article | First Published: December 18, 2019

Women with stress urinary incontinence can be offered an operation with mid-urethral sling. First, Tension- free vaginal tape was invented. Some years later, because of concerns about complications associated with this operation, the other minimally invasive procedure using the trans obturator procedure was introduced by Dr. J. de Leval in 2003. Since then, the diversity in methods gave rise to a discussion of both efficacy, complications and reoperations. In Denmark, the professional discussion about Tension-free Vaginal Tape Obturator is ongoing, which is an important reason for evaluating t...

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