Spontaneous Regression of Hepatic Diffuse Large B-cell Lymphoma in HIV and HCV Positive Patient: A Novel Case Study
Albert Alhatem, Saiaditya Badeti, Chen Liu, Dongfang Liu and Donghong Cai
Article Type: Case Report | First Published: October 23, 2019
Diffuse large B-cell lymphoma (DLBCL) rarely occurs in the liver. Spontaneous regression of this tumor is extremely rare. We are reporting the first case of hepatic DLBCL, and we are reviewing the English literature for cases of spontaneous regression of DLBCL and cancer in general. A 60-year-old gentleman with a history of HIV and HCV infections presented with an incidental liver mass. He was diagnosed with DLBCL germinal cell type with high grade features based on the results of pathological/cytogenetics studies. He started HCV and HIV medication but refused lymphoma chemotherapy. Radiologic...
Optic Perineuritis Secondary to Sjogreen’s Syndrome: Case Report
Juliana Emy Tolachinski Oikawa, Julia Gomes Leite de Souza, Vitoria Caroline Cardoso Ferreira, Paulo Roberto Wille, MD, PhD, Laura Fiuza Parolin, MD and Marcus Vinícius Magno Goncalves, MD, PhD
Article Type: Case Report | First Published: November 04, 2019
Optic perineuritis (OPN) is a rare inflammatory disease involving the optic nerve sheath, causing pain and disc edema and is often bilateral. The diagnosis of OPN is commonly based on magnetic resonance imaging (MRI) findings and clinical features. In MRI it is possible to visualize a circumferential enhancement around the intraorbital optic nerve with preservation of the nerve itself (doughnut sign). This is better seen in contrast-enhanced and suppressed coronal MRI sequences with fat. Magnetic resonance imaging may also show enhancement of orbital fat and slight increase in extraocular musc...
Levo-Bupivacaine vs. Ropivacaine for Post-Operative Pain Relief after Pre-Emptive Intraperitoneal Instillation in Laparoscopic Appendicectomy
Thiruselvi Subramaniam and Tan Ann Jee
Article Type: Original Article | First Published: October 26, 2019
Pain in the immediate postoperative period is found to be less after laparoscopic than after conventional surgical techniques. Ropivacaine is often in favour of Bupivacaine to avoid the risks of toxicity. Levo-bupivacaine, a safer version of bupivacaine is a contender to Ropivacaine. We compare the pain relief provided by Ropivacaine and Levo-bupivacaine instilled intra-abdominally during laparoscopic surgery for acute appendicitis. This is a double blinded randomized placebo- controlled study conducted on 120 patients in a public hospital over a period of 10 months. Using patient control anal...
Skull Metastasis in Prostate Cancer: A Compilation of Four Cases along with Review of the Literature
Brahima KIRAKOYA Fasnewinde Aristide KABORE, Babagana Mustapha ABUBAKAR, Mohamed SIMPORE, Bienvenue Desire KY and Aïssata OUEDRAOGO
Article Type: Research Article | First Published: November 06, 2019
Skull metastasis in prostate cancer is rare and is seen in advanced cases. We study four cases seen in our facility with the aim of identifying challenges in making diagnosis and treatment of these patients. We also reviewed the literature. This study involved four men age 55, 65, 66 and 69 years. In two cases, the skull metastases were discovered during evaluation for primary skull swelling, no lower urinary tract symptoms (LUTS) at presentation. In the other two cases, skull metastases were discovered when the patients were evaluated for metastases after the diagnosed prostate cancer. There ...
Hormonal Evaluation of Adrenal Tumors: What the Common General Practitioner Should Know
Bruno Costa do Prado, Gustavo Silva Schafascheck and Alana Rocha Puppim
Article Type: Research Article | First Published: October 17, 2019
Adrenal tumors may be a benign finding or imply a high level of morbidity and mortality due to their hormonal activity, or to a possible malignant histology. Medical literature indicates that this condition is due to the improvement of the technique and dissemination in a wide range of imaging methods, increasing considerably the diagnosis of adrenal nodules and its immediate treatment. When treating a patient with adrenal tumors, the main concern of the professional should be to establish if the lesion is a malignant neoplasm and if there is some hormonal functioning, which are two occurrence...
The Prevalence of Work-Related Muskuloskeletal Disorders (WRMSDs) and Related Factors among Occupational Disease Clinic Patients
Zeynep DOGRUL, MD, Nejdiye MAZICAN, MD and Meral TURK, Prof. Dr.
Article Type: Research Article | First Published: October 28, 2019
Work-related musculoskeletal disorders (WRMSDs) are one of the common health problems of employees. WRMSDs are impairments of bodily structures such as muscles, joints, tendons, ligaments, nerves, bones and the localised blood circulation system, that are caused or aggravated primarily by work and by the effects of the immediate environment in which work is carried out. The aim of this study is; to determine the prevalence of work related musculoskeletal disorders and the related factors such as socio-demographic characteristics and working conditions among occupational disease outpatient clin...
Coronary Artery Involvement Following Kawasaki Disease: A Case Report of a 5 Month Old African Infant
Tumwebaze Hilda, Ndagiire Emma, Namuyonga Judith, Twalib Aliku, Lwabi Peter and Lubega Sulaiman
Article Type: Case Report | First Published: November 07, 2019
Kawasaki disease (KD) is an acute systemic vasculitis which progresses to cause coronary artery abnormalities as a complication. Echocardiographic and cardiac angiographic data indicate that 20-40% of untreated KD patients develop coronary artery abnormalities. However, majority of the lesions regress over time. Timely treatment with high dose intravenous immunoglobulins (IVIG) and high dose of aspirin has been found reduce the incidence of developing coronary artery aneurysms to 2%-3%. Data on KD in the African region is unavailable. We present a case of a 5 month old infant that presented at...
Relationship Between Mean Platelet Volume-to-Platelet Count Ratio and the Presence and Severity of Coronary Artery Ectasia
Ramazan Asoglu and Emin Asoglu
Article Type: Research Article | First Published: September 28, 2019
Atherosclerosis plays an essential role in the etiopathogenesis of coronary artery ectasia (CAE). The mean platelet volume/platelet count (MPV/PLT) ratio is a new biomarker, and increased MPV/PLT ratio was a predictor of cardiovascular mortality in patients with the acute coronary syndrome. We aimed to assess the association between the CAE and MPV/PLT ratio. The present study included 50 patients with CAE and 45 healthy subjects prospectively. The CAE was defined as dilation of the coronary artery > 1.5-fold the diameter of the adjacent normal coronary vessels The severity of isolated CAE was...
Percutaneous Coronary Intervention in a Cancer Patient with Dextrocardia and Situs Inversus
Article Type: Case Report | First Published: October 25, 2019
Although dextrocardia occurs rarely, the incidence of coronary artery disease is similar to the general population. Few cases of coronary angiography and percutaneous coronary intervention (PCI) in patients with dextrocardia have been reported. Because of unfamiliarity with performing catheterization, transradial coronary angiography has seldom been performed in a patient with dextrocardia. To the best of our knowledge, this is the first report of successful coronary angiography and ad hoc coronary stenting in a cancer patient with dextrocardia with situs inversus in Lebanon. We successfully p...