ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

Recent Publication

A Plausible “Penny” Costing Effective Treatment for Corona Virus - Ozone Therapy
"Novel coronavirus" SARS-CoV-2 is rapidly spreading worldwide with a significant mortality rate. There is real threat of a global pandemic of an easily transmissible disease, with a significant morbidity and mortality, from this epidemic if not another in the future. According to the World health Organization, SARS-CoV-2 carries at least a 14-day incubation period.

ClinMed Archive

4
3
6
7

Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

ICV

Check the Index Copernicus Values of ClinMed Journals

Content Registration

All Articles published with ClinMed will be registered with Crossref and DOI will be asigned to each article.
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3001/2/1/1017

Intravenous Infusion of Ginsenoside Rb1 Ameliorates Compressive Spinal Cord Injury through Upregulation of Bcl-xL and VEGF

Pengxiang Zhu, Ryuji Hata, Kimihiko Nakata, Fang Cao, Keiichi Samukawa, Hiroko Fujita and Masahiro Sakanaka

Article Type: Research Article | First Published: January 15, 2015

Red ginseng root (Panax Ginseng C.A. Meyer) has been used clinically by many Asian people for thousands of years without any detrimental effects. Subsequent studies that focused on gRb1-induced expression of gene products responsible for neuronal death or survival revealed that gRb1 upregulated the expression of not only Bcl-XL, but also a potent angiogenic and neurotrophic factor, vascular endothelial growth factor (VEGF) at 7 days after SCI. Ginsenoside Rb1 (gRb1), with putative anti-apoptotic, angiogenic and neurotrophic actions, is a candidate agent for the treatment of patients with acut...

 Open Access DOI:10.23937/2378-3001/2/1/1016

Cortical Diffusion Restriction as the Single Abnormality on MRI in Creutzfeldt-Jakob disease

Johnny Samijn, Alisha Godschalk, Rezan Demir and Esther Brusse

Article Type: Case Report | First Published: January 12, 2015

Creutzfeldt-Jakob disease (CJD) is a rare neurodegenerative disease characterized by rapidly progressive dementia, ataxia and myoclonus. MRI is an important tool in discriminating CJD from other dementias. Among mimics of CJD are rapidly evolving Alzheimer's disease, vascular dementia, frontotemporal dementia and paraneoplastic or immune-mediated limbic encephalitis. A CJD diagnosis can be missed and strong clinical suspicion is not always confirmed on autopsy. Typical imaging findings are white matter abnormalities in the thalamus, the striatum and progressive atrophy....

 Open Access DOI:10.23937/2378-3001/2/1/1015

Basis and Argument into the Work

Roberto Rodrigues, George Perry and Robert Petersen

Article Type: Review Article | First Published: January 12, 2015

This synopsis is a brief report about the conclusions in which we have engaged from considering that Alzheimer's disease, cognitive impairment and aging could progress with analogous molecular signaling, with no frontiers between their phenotypes. We have also proposed that chronic depression, with or no anxiety and/or stress comorbidindication may interact with these AD manifestations - already product of genomic vulnerability - at any stage of the disease. A known example may bemutant short alleles on the depression genes corresponding to the synthesis of a series of neurotransmitter transpo...

 Open Access DOI:10.23937/2378-3001/2/1/1014

Caspase Cleaved Tau in Alzheimer's Disease: A Therapeutic Target Realized

Troy T. Rohn

Article Type: Hypothesis | First Published: January 12, 2015

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by an array of symptoms affecting memory and cognition. Some common symptoms of AD include memory loss that disrupts daily life, challenges in planning or solving problems, confusion with time or place, and changes in mood and personality. Central dogma to the etiology of AD is the beta-amyloid cascade, which stipulates that beta-amyloid in oligomeric forms represents the earliest step in a cascade eventually leading to the formation of senile plaques and neurofirillary tangles (NFTs) and neurodegeneration....

 Open Access DOI:10.23937/2378-3672/1410003

Analyze the Levels of Immunoglobulins IgG and IgM in Elderly and Youngs

Samia Macedo Queiroz Mota Castellao Tavares, Wilame de Lima Bravo Junior and Jessica Lissandra Alves Leite

Article Type: Research Article | First Published: January 16, 2015

The aging process is complex and affects a variety of functions, including lower defense capability of the immune system. The immune activity, as most of physiological functions, decreases with age. The principal alterations in humoral immune response are associated with concentration of immunoglobulins, amount and activity of B cells and also the changes in the affinity of the antibodies. The current study aimed to analyze the levels of IgG and IgM antibodies of elderly and young people and to investigate the statistical difference between the groups. The research was a descriptive study and ...

 Open Access DOI:10.23937/2378-3656/1410014

Atrial Fibrillation Triggered by Theophylline: a Case Report Treated with 'Pill in the Pocket'

Ekrem Sahan and Suzan Sahan

Article Type: Case Report | First Published: January 04, 2015

Atrial fibrillation (AF) is the most common sustained arrhythmia and the prevalence of AF increases with age. Ageing, hypertension, coronary artery disease, heart failure, diabetes mellitus, valvular heart diseases, congenital heart defects, thyroid dysfunctions, chronic obstructive pulmonary disease, drugs and alcohol are associated with atrial fibrilliation. New-onset AF can be converted to sinus rhythm. 'Pill in the Pocket' administration can be effective in new-onset AF. Herein, we present a new-onset AF was triggered by drug (theophylline) and converted with oral propafenone instead of el...

 Open Access DOI:10.23937/2377-3634/1410017

Effect of Alogliptin, a DPP-4 Inhibitor, on Markers of Lipid Metabolism in Type 2 Diabetic Patients

Yuzuru Kishitani, Hideyuki Okuda, Daisuke Kinoshita, Kanyun Hata and Toshihiko Kawasaki

Article Type: Research Article | First Published: December 31, 2014

Background: DPP-4 inhibitor has been shown to improve not only blood glucose levels but also dyslipidemia, but the effect remains controversial. Further, there are few reports regarding the influence on Apo B, Apo A-1 and Apo B/Apo A-1 in alogliptin. Objective: Using the alogliptin, we focused on Apo B and Apo A-1, in addition to LDL-C, HDL-C and TG, and investigated the effect of alogliptin on markers predicting cardiovascular events, such as Apo B/Apo A-1 and LDL-C/Apo B....

 Open Access DOI:10.23937/2377-3634/1410016

Correlations of OSA Severity and Carotid Intima-Media Thickness in Patients with Type 2 Diabetes

Jiang Xiao-zhen, Xi Feng, Chen Rui-Hua, Jiang Quan and Zou Yu-Feng

Article Type: Review Article | First Published: December 29, 2014

Aim: To determine whether carotid intima-media thickness (C-IMT) was elevated in diabetic patients with Obstructive Sleep Apnea (OSA), and correlations of OSA severity with IMT and other clinical characteristics. Materials and methods: The study subjects were composed of 36 diabetic patients with OSA (group A), and 34 patients without OSA (group B). In both groups, blood lipids, fasting blood glucose, glycated hemoglobin, Epworth Sleepiness Scale, C-IMT and carotid resistance index (C-RI) were assessed, and results of sleep study were collected to investigate possible correlations with IMT and...

 Open Access DOI:10.23937/2377-9004/1410019

Conservative Management of Uterine Artery Pseudoaneurysm Rupture with Rectal Fistula after Laparoscopic Myomectomy and Review of the Literature

Gabbi L, Petrocelli F, Di Domenico S, Ferrero S and RemorgidaV

Article Type: Case Report | First Published: December 17, 2014

Late uterine hemorrhage caused by uterine artery pseudoaneurysm is a rare but life-threatening complication after uterine surgery. The association of uterine pseudoanerysm rupture causing rectal fistula has not been reported in literature as well as its management. Herein we report a case of massive late uterine bleeding and rectal bleeding after laparoscopic myomectomy. A 43 year old Caucasian nulliparous woman underwent laparoscopic excision of 8 cm posterior intramural myoma. One month later she developed acute abdominal pain and proctorrhagia....

 Open Access DOI:10.23937/2378-3001/1/1/1013

The Importance of Stimulation Cycle in Vagus Nerve Stimulation for Drug-Resistant Epilepsies- Our Experience and Literature Review

Nicola Montano, Filomena Fuggetta, Fabio Papacci, Rina Di Bonaventura, Mario Meglio and Gabriella Colicchio

Article Type: Review Article | First Published: December 17, 2014

The impact of stimulation cycle on the outcome of patients submitted to Vagal Nerve Stimulation (VNS) has been only marginally investigated in the literature. Nonetheless this is an important factor in term of tolerability of side effects, duration of generator and costs of therapy. Here the role of this parameter was evaluated on 21 patients who underwent to VNS implant at our Institution from January 1994 to February 2011 and responded to VNS (they reported a stable decrease of seizure number at least of 50%). We studied 3 stimulation cycles....

Why ClinMed?

Preservation of author rights
Global followership
Noncommercial objectives
Neutral and unbiased publishing process
Reprints issued accross the world
Timely submission for indexing
Published with CrossMark® policy

Editors' Picks

Can Genetic Testing Provide Information to Develop Customized Nutrigenomic..
Pubmed ID:26225358 | PMC ID:PMC4516390
Acute Ovarian Insufficiency and Uterine Infarction Following Uterine Artery..
Pubmed ID:26523290 | PMC ID:PMC4623578
Challenges of Fertility Sparing Ovarian Surgery Imposed by Krukenberg..
Pubmed ID:26366440 | PMC ID:PMC4563814
Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral..
Pubmed ID:27398405 | PMC ID:PMC4936830
Hypothesizing that a Pro-Dopaminergic Regulator (KB220z™ Liquid Variant)..
Pubmed ID:29034323 | PMC ID:PMC5638455
Titanates and Titanate-Metal Compounds in Biological Contexts..
Pubmed ID:26430701 | PMC ID:PMC4587770
MyHEART: A Non Randomized Feasibility Study of a Young Adult..
Pubmed ID:28191544 | PMC ID:PMC5300088
Exenatide Effects on Cardiometabolic Risk and Weight in Adolescents..
Pubmed ID:27182560 | PMC ID:PMC4864000
A New Animal Model to Study Endogenous Cardiotonic Steroids and the Progression..
Pubmed ID:26457335 | PMC ID:PMC4599712
Common Genetic Variation in Circadian Rhythm Genes and Risk of..
Pubmed ID:26807442 | PMC ID:PMC4722961
Active Hexose Correlated Compound Activates Immune Function to Decrease..
Pubmed ID:27790645 | PMC ID:PMC5079436
The Extraction, Anticancer Effect, Bioavailability, and..
Pubmed ID:27790646 | PMC ID:PMC5079443
Kyphosis and Sleep Characteristics in Older Persons: The Rancho..
Pubmed ID:28480455 | PMC ID:PMC5419044
Suppression of Experimental Arthritis through AMP-Activated Protein..
Pubmed ID:26120598 | PMC ID:PMC4479345
Aspirin-Triggered Resolvin D1 Versus Dexamethasone in the Treatment of..
Pubmed ID:27110599 | PMC ID:PMC4841619
Elder Mistreatment and its Subtypes across Different Sociodemographic and..
Pubmed ID:26973979 | PMC ID:PMC4786076
Balance and its Clinical Assessment in Older Adults - A Review..
Pubmed ID:26942231 | PMC ID:PMC4773046
Caregiver Abuse of Chicago Chinese Older Adults in a Community..
Pubmed ID:27606358 | PMC ID:PMC5008847
The Relationship of Older Adults' Physical Pain to Depression and..
Pubmed ID:27642644 | PMC ID:PMC5023019
Sphingosine 1-Phosphate Receptor 2 Regulates the Migration,..
Pubmed ID:27275017 | PMC ID:PMC4888913
Mammary Epithelial Cell Lineage Analysis via the Lyon's Hypothesis..
Pubmed ID:27453956 | PMC ID:PMC4957014
Epigenetic Loss of MLH1 Expression in Normal Human Hematopoietic Stem Cell..
Pubmed ID:27570841 | PMC ID:PMC4996274
Long-Term Function, Pain and Medication Use Outcomes of Radiofrequency..
Pubmed ID:26005713 | PMC ID:PMC4440581
Caspase Cleaved Tau in Alzheimer's Disease: A Therapeutic Target..
Pubmed ID:25639474 | PMC ID:PMC4308811
Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?..
Pubmed ID:26550607 | PMC ID:PMC4634668
Differences in ME and CFS Symptomology in Patients with Normal and..
Pubmed ID:28713856 | PMC ID:PMC5510614
Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive..
Pubmed ID:26005715 | PMC ID:PMC4440485
A Derivative of Differentiation-Inducing Factor-3 Inhibits PAK1..
Pubmed ID:26688830 | PMC ID:PMC4682050
Overcoming Endocrine Resistance in Hormone-Receptor Positive Advanced..
Pubmed ID:26726315 | PMC ID:PMC4697745
Zinc Ionophore (Clioquinol) Inhibition of Human ZIP1-Deficient Prostate..
Pubmed ID:26878064 | PMC ID:PMC4751054
Electron Microscopic Analysis of Silicate and Calcium Particles..
Pubmed ID:27158665 | PMC ID:PMC4858188
Effects of chest physical therapy in patients with non-tuberculous mycobacteria
Pubmed ID:28804763 | PMC ID:PMC5552049
A Community-Based Exercise and Support Group Program Improves Quality..
Pubmed ID:26640827 | PMC ID:PMC4667740
Four Weeks of Balance Training Does Not Affect Ankle Joint Stiffness in Subjects..
Pubmed ID:27642647 | PMC ID:PMC5025258
Social Ecology and Diabetes Self-Management among Pacific Islanders..
Pubmed ID:28736764 | PMC ID:PMC4516390
Examining Characteristics of Hospitalizations in Heart Failure Patients: Results..
Pubmed ID:28736765 | PMC ID:PMC5517048

Featured Articles

Imaging Modality and Management of Hepatic Injury in the Trauma Setting

Anthony J Brusnahan

DOI: 10.23937/2469-5777/1510080



An Atypical Soft Tissue Mass on the Dorsum of the Foot: A Case Report

Susan Vaughan Kratz, OTR, CST-D

DOI: 10.23937/2643-3885/1710040



A Novel Oblique Impact Test Rig for Testing Helmet

Daniel E Abram, Adrian Wikarna, Farid Golnaraghi and G Gary Wang

DOI: 10.23937/2469-5718/1510158



Acute Simultaneous Renal and Ovarian Vein Thrombosis Mimicking Renal Colic and Associated with Factor V Leiden: Case Report and Review of Literature

Chahid Farah, Sabine Imad, Rachelle Abboud, Fady Nader, Rahil Zeaiter, Boutros Youssef, Karen Nicolas, Mireille Rizkallah, Alain Khalaf and Tony El Murr

DOI: 10.23937/2378-3656/1410297


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin