ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

Recent Publication

A Plausible “Penny” Costing Effective Treatment for Corona Virus - Ozone Therapy
"Novel coronavirus" SARS-CoV-2 is rapidly spreading worldwide with a significant mortality rate. There is real threat of a global pandemic of an easily transmissible disease, with a significant morbidity and mortality, from this epidemic if not another in the future. According to the World health Organization, SARS-CoV-2 carries at least a 14-day incubation period.

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 Open Access DOI:10.23937/2378-346X/1410011

Generation of Retinal Progenitor Cell Sheets which Differentiate into Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones

Noboru Suzuki, Jun Shimizu, Chieko Hirotsu, Erika Takada, Nagisa Arimitsu, Yuji Ueda, Naruyoshi Fujiwara, Tomoko Suzuki and Kenji Takai

Article Type: Research Article | First Published: February 05, 2015

We previously reported successful establishment of retinal progenitor cell clones. Here, we cultured them on temperature reversible gelation polymer, with supplementation of several chemokines. The retinal progenitor cell clones formed a cell sheet with extension of their axon like processes. RT-PCR of the cell sheets after two week culture, they were positive for retinal ganglion cell markers, bipolar cell markers, and photoreceptor cell markers. Immunohistochemistry suggested that the cell sheets contained photoreceptors and synaptic connection was observed within the sheet. We found that in...

 Open Access DOI:10.23937/2378-3419/2/1/1013

Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive Breast Cancer Associates with Postmenopausal Body Size and Recreational Physical Activity

Lauren E. McCullough, Jia Chen, Alexandra J. White, Xinran Xu, Yoon Hee Cho, Patrick T. Bradshaw, Sybil M. Eng, Susan L. Teitelbaum, Mary Beth Terry, Gail Garbowski, Alfred I. Neugut, Hanina Hibshoosh, Regina M. Santella, Marilie D. Gammon

Article Type: Original Article | First Published: February 09, 2015

Introduction: Breast cancer, the leading cancer diagnosis among American women, is positively associated with postmenopausal obesity and little or no recreational physical activity (RPA). However, the underlying mechanisms of these associations remain unresolved. Aberrant changes in DNA methylation may represent an early event in carcinogenesis, but few studies have investigated associations between obesity/RPA and gene methylation, particularly in postmenopausal breast tumors where these lifestyle factors are most relevant. Methods: We used case-case unconditional logistic regression to estim...

 Open Access DOI:10.23937/2469-5726/1510001

Subchondral Bone: An Emerging Target for Treatment of Osteoarthritis

Lukas A. Holzer

Article Type: Editorial | First Published: February 15, 2015

Osteoarthritis (OA) is a long-term chronic disease that is characterized by the deterioration of cartilage in joints resulting in stiffness, pain and impaired range of motion. OA is a disease that is associated with ageing. However, there are various factors e.g. obesity, lack of exercise, genetical abberations, occupation, trauma and gender that contribute to progression of OA. Osteoarthritis is the most common form of arthritis. The World Health Organization estimates that globally 25% of adults over the age of 65 years have clinically symptomatic osteoarthritis of any joint....

 Open Access DOI:10.23937/2572-4037.1510002

Narcissism: It's more Complex than High Self-Esteem

Marion Wallace

Article Type: Editorial | First Published: January 30, 2015

Narcissism is often used synonymously with high or inflated selfe-steem. Indeed, narcissism is illustrated by individuals with grandiose self-views and a need for admiration. The origins of the term stem from Greek mythology where a young man named Narcissus became enamored with his reflection. However, individuals with higher levels of narcissistic traits make up a unique combination of high and vulnerable self-esteem. Since narcissism is more complex than high self-esteem, individuals with higher levels of narcissism may not see the benefits typically rewarded to those with stable high self-...

 Open Access DOI:10.23937/2469-5696/1410006

The Study of the Mechanism of Action of the Newly Synthesized Direct Anticoagulant of Thiazoline Ammonium -4-Chlorophenyl-2-Hydroxy-4-Oxo-2-Butenoate

Starkova AV, Syropyatov B Ya, Sobin FV and Pulina NA

Article Type: Case Report | First Published: February 08, 2015

The aim of this research is to study the mechanism of action of the newly synthesized substance - Thiazoline Ammonium 4-Chlorophenyl-2-Hydroxy-4-Oxo-2-Butenoate (FS-169), which possesses the direct anticoagulant activity. The research was conducted with the use of 'АPG4-02-P' coagulometer. For the purposes of the study the rabbit plasma was used. The results show that FS-169 effectively changes Partial thromboplastin time and prothrombin time indicators. However, FS-169 has no influence on Thrombin time. The substance also does not affect the activity of II and V coagulation factors. FS-...

 Open Access DOI:10.23937/2572-4010.1510001

Anti-Obesity Drugs: A Necessary Part of Treatment

Raquel Cristina Lopes Assis Coelho

Article Type: Editorial | First Published: January 29, 2015

Worldwide obesity prevalence has nearly doubled since 1980. Obesity is reaching epidemic proportions worldwide and it is correlated with various comorbidities, among which the most relevant are diabetes mellitus, arterial hypertension, and cardiovascular diseases. Obesity management is a modern challenge because of the rapid evolution of unfavorable lifestyles. Due to numerous co-morbidities, obesity represents a serious health and socioeconomic problem worldwide....

 Open Access DOI:10.23937/2378-3516/1410014

Does the Body Mass Index Affect the Success of Noninvasive Mechanical Ventilation in Patients with Acute Hypercapnic Respiratory Failure?

Esmehan Akpinar, Serdar Akpinar and Nazire Ucar

Article Type: Research Article | First Published: February 15, 2015

Objective: Obesity has many negative effects on lung functions. It is not yet clear whether body mass index (BMI) affects the success of noninvasive mechanical ventilation (NIMV). The aim of this study was to investigate the differences in NIMV strategies, on the basis of BMI, in patients with acute hypercapnic respiratory failure and the effect of BMI on the success of NIMV. Methods: A total of 86 patients who had acute hypercapnic respiratory failure were enrolled consecutively....

 Open Access DOI:10.23937/2572-4037.1510001

Assistive Technology for Children with Multiple Disabilities

Fabrizio Stasolla

Article Type: Editorial | First Published: January 24, 2015

Children with severe to profound developmental and/or multiple disabilities (i.e. combination of sensorial, intellectual and motor disabilities) are commonly described as quite passive and isolated, with few opportunities to interact positively with the surrounding world, dues to their general conditions hampering their social image, status and overall desirability. Thus, those children present a very limited behavioral repertoire, often exhibiting lack of speech, failing locomotion, stereotypic behaviors, unawareness of sphincter control, withdrawal....

 Open Access DOI:10.23937/2378-3001/2/1/1020

Psychogenic Nonepileptic Seizures: Diagnostic Challenges and Treatment Dilemmas

Taoufik Alsaadi and Tarek M Shahrour

Article Type: Review Article | First Published: February 12, 2015

Psychogenic Nonepileptic Seizures (PNES) are episodes of movement, sensation or behavior changes similar to epileptic seizures but without neurological origin. They are somatic manifestations of psychological distress. Patients with PNES are often misdiagnosed and treated for epilepsy for years, resulting in significant morbidity. Video-EEG monitoring is the gold standard for diagnosis. Five to ten percent of outpatient epilepsy populations and 20 to 40 percent of inpatient and speciality epilepsy center patients have PNES. These patients inevitably have comorbid psychiatric illnesses, most co...

 Open Access DOI:10.23937/2378-3516/1410013

The Use of Independent Lung Ventilation for Unilateral Pulmonary Hemorrhage

Ajit A. Sarnaik

Article Type: Case Report | First Published: February 08, 2015

Independent Lung Ventilation (ILV) has been used in the critical care setting as a rescue therapy for differential lung disease. The purpose of anatomic separation of the lungs is to prevent blood, purulent secretions, or other debris from one lung from contaminating the other lung. Physiologic separation of the lungs allows different ventilator strategies to be applied to each lung. We report the case of the successful use of ILV in a man with congenital heart disease with severe right sided pulmonary hemorrhage in which the left lung was relatively disease-free. By use of high-pressure 'open...

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Imaging Modality and Management of Hepatic Injury in the Trauma Setting

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Acute Simultaneous Renal and Ovarian Vein Thrombosis Mimicking Renal Colic and Associated with Factor V Leiden: Case Report and Review of Literature

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Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin