ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.



  Last Updated: December 01, 2020

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2378-3516/1410097

Correlation between Pentraxin-3 and Left Ventricular Diastolic Dysfunction in Obstructive Sleep Apnea

Jie-Ru Li, Xiu-Hua Gao, Ju-Qiang Han, Wen-Yan Luo and En-Sheng Ji

Article Type: Original Article | First Published: November 23, 2018

Obstructive sleep apnea (OSA) is one of independent dangerous factors for cardiovascular disease including heart failure. Recent studies demonstrated that left ventricular diastolic dysfunction (LVDD) and pentraxin-3 (PTX-3) are early signs for development of heart failure. The objective of our study was to estimate the relation between OSA severity and LVDD and PTX-3. Sixty-six OSA patients and 25 healthy people who underwent polysomnography to diagnose OSA were enrolled. Ninety-one participant...

 Open Access DOI:10.23937/2378-3648/1410040

HLA DRB1*/DQA1*Alleles and TNF-alpha G308A Polymorphism Protect against Neuromyelitis Optica in the Cuban Population

Fernandez-de-Cossio ME, Cintado A, Nazabal M, Camacho H, Diaz T, Villarreal A, Ale M, Grass D, Cervantes-Llanos M, Pavon-Fuentes N, Benitez JV, Cabrera-Gomez JA, Diaz de la Fe A and Penton-Rol G

Article Type: Research Article | First Published: November 23, 2018

Neuromyelitis optica (NMO) is a complex immune-mediated disease whose prevalence differs among ethnic groups, most likely due to genetic factors. The presence of the Human Leucocyte Antigens (HLA) extended haplotype is a risk for NMO. The tumor necrosis factor-alpha (TNF-a) is believed to play a role in NMO pathogenesis. Although single nucleotide polymorphisms (SNPs) in the TNF-a promoter region (pTNF-a) has been shown to influence levels of TNF-a production, such an association is not evident ...

 Open Access DOI:10.23937/2572-4037.1510036

A Critical Review and Future Directions for Research: Personality and Social Entrepreneurial Success

Shilpi Sharma and Sahni SP

Article Type: Review Article | First Published: November 23, 2018

Probably millions of people across the world dream of starting their own business, a fraction of them may gather the courage and resources to pursue their ambitions, and still, even a smaller fraction of those may persevere through the challenges and inevitable disappointments, entrepreneurial process may present; and finally, a very small number of entrepreneurs succeed in achieving their objectives. What determines the difference in behaviours and attitudes of these individuals? Why some never...

 Open Access DOI:10.23937/ijfa-2017/1710019

Total Ankle Replacement: Indications, Rehabilitation and Results

Marco Massobrio, Giovanni Pellicano, Valter Santilli and Lucrezia Tognolo

Article Type: Research Article | First Published: November 22, 2018

Even though fusion is the main form of treatment for end-stage osteoarthritis (OA) of the ankle, total ankle replacement (TAR) is increasingly being recognized as an effective alternative procedure, with favorable clinical results and improved quality of life. However, the results have been disappointing compared to those of hip and knee arthroplasty. In fact, the ankle is a more complex joint and its biomechanics and kinematics are strongly influenced by neighboring joints. The ankle joint comp...

 Open Access DOI:10.23937/2572-4215.1510015

Fractional Anisotropy Brain Changes in Spasticity after Peripheral Injections of Botulin

Miguel Angel Bertoni, Mohammed Sakel and Ali Hojjatoleslami

Article Type: Research Article | First Published: November 22, 2018

Seven subjects with spasticity that developed 2-22 years after cerebrovascular accidents (CVA) were studied with 3T MRI of the brain including diffusion tractography (DTI) and fractional anisotropy (FA) measurements of the white matter of the corticospinal tracts (CST), corpus callosum (CC) and cerebral lobes of the affected and contralateral sides prior and after the injection of botulin toxin at the contours of peripheral nerves of the affected side....

 Open Access DOI:10.23937/2469-5866/1410025

Cognitive Rehabilitation Improves Performance of Individuals with Mild to Moderate Traumatic Brain Injury: A Review of Comprehensive Neuropsychological Services as a Model Approach

Cheryl A Frye, Anton Hardy and Maria Lifrak

Article Type: Review Article | First Published: November 22, 2018

Traumatic Brain Injuries (TBI) can result in physical, cognitive and emotional symptoms and the constellation of sequelae that can linger for years and is termed post-concussion syndrome (PCS). For these ailments, therapy is available to help individuals recover; however, it is controversial whether cognitive rehabilitation can improve or forestall lost or damaged abilities. It is important to clarify this because insurances companies can be reluctant to pay for this treatment. To test the effic...

 Open Access DOI:10.23937/ijcb-2017/1710003

Employing Kinect for Cognitive-Motor Assessment: A Feasibility Study

Uzi Levi, Roni Laslo-Roth and Eyal Rosenstreich

Article Type: Research Article | First Published: November 21, 2018

This study examined the feasibility of the Microsoft Kinect sensor for assessing mediolateral trunk sway and its associations with cognitive abilities. To this end, young adults and elderlies were sampled and performed various gait and balance tasks under single- and dual-task paradigms. Although reliable, Kinect's ability to assess cognition through movement was not conclusive. Specifically, the Kinect distinguished between young- and old-adults gait, but not between young-adults with and witho...

 Open Access DOI:10.23937/2378-3672/1410033

Biomarkers in Relation to Disease Manifestations in Psoriatic Arthritis

Kristina Juneblad, Solbritt Rantapää-Dahlqvist and Gerd-Marie Alenius

Article Type: Research Article | First Published: November 21, 2018

Two-hundred and seventy-four patients with established disease and 30 healthy controls were included in this cross-sectional study. Thirty-nine different serological biomarkers were investigated in relation to disease activity, disease manifestations and in comparison with controls. In addition to standard statistical methods, orthogonal partial least squares discriminant analysis (OPLS-DA) was used to investigate different phenotypes of PsA....

 Open Access DOI:10.23937/ijfa-2017/1710018

Does the Screw Grip Affect the Outcome of Screw Fixation of Malleolar Fractures?

Stamatios A Papadakis, Athanasios Koutroufinis, Dimitrios Pallis, Athanasios Badekas, Konstantinos Kateros, Olga Savidou and George A Macheras

Article Type: Research Article | First Published: November 21, 2018

The study -which is the first clinical according to the literature- included 136 patients with surgical fractures of the ankle. Patients presenting any evident factors influencing porosis as well as open fractures were excluded. Fibula reduced anatomically and fixed by a 1/3 tubular plate placed laterally. Proximal screws had bicortical fixation grip strength while distal screws had only unicortical. Screws with a reduced fixation grip strength during insertion were left in place. Numbers were a...

 Open Access DOI:10.23937/2572-3235.1510041

Contemporary Management of Meningiomas with Radiosurgery

Selcuk Demiral, Ferrat Dincoglan, Omer Sager, Bora Uysal, Hakan Gamsiz, Fatih Ozcan, Bahar Dirican and Murat Beyzadeoglu

Article Type: Review Article | First Published: November 21, 2018

Meningiomas are the most common intracranial benign tumors. While an indolent natural history is typical for benign meningiomas, a wide spectrum of symptoms may occur depending on lesion location and proximity to critical neurovascular structures. A multidisciplinary approach may be warranted for optimal management of meningiomas. In the scarcity of prospective, randomized controlled studies to dictate treatment algorithms, decision making for treatment is based primarily on mostly retrospective...

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