ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.



  Last Updated: May 06, 2021

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2643-4474/1710061

COVID-19 Associated with Severe Intracranial Hemorrhage in Previously Healthy Patients

Ioan Alexandru FLORIAN, Magdalena BALACI, Teodora Larisa TIMIȘ, Cristina Caterina ALDEA, Laura MUREȘAN, Oana Maria RADU and Ioan Stefan FLORIAN

Article Type: Case Report | First Published: February 27, 2021

The neurological complications of COVID-19 are still under scrutiny, stroke and intracranial hemorrhages being the most commonly described events. Hemorrhagic stroke in previously healthy patients and with a normal coagulative status has only rarely been described. We present three males aged 30, 57 and 38 respectively, who suffered from intracranial hemorrhages, having been diagnosed with COVID-19, with no medical history and under no previous medication. They were all operated via external ven...

 Open Access DOI:10.23937/2474-3658/1510195

The COVID-19 Burden or Tryptophan Syndrome: Autoimmunity, Immunoparalysis and Tolerance in a Tumorigenic Environment

Luiz Gonzaga Francisco de Assis Barros D’Elia Zanella and Luciana de Lima Galvão

Article Type: Review Article | First Published: February 27, 2021

SARS-CoV-2, a new virus, which has been causing the catastrophic pandemic in the world in 2020, triggers numerous physiologic changes in humans, with potentially fatal evolution due to COVID-19. COVID-19 can trigger immunoparalysis with deep and silent immunosuppression and a state of tolerance that may elicit opportunities for neoplastic transformation or latent infectious diseases. In addition, all neurologic or psychiatric symptoms have been observed - as clinically present in usual diseases,...

 Open Access DOI:10.23937/2474-3658/1510192

Effect of Hydroxychloroquine or Chloroquine and Azithromycin on COVID-19 Patients' Recovery and Mortality: Evidence from a Hospital Based Retrospective Cohort Study Conducted in Burkina Faso

Adama Baguiya, MD, Msc, Armel Poda, MD, Kadari Cissé, MD, Msc, Apoline K Sondo, MD, Boukary Ouedraogo, MD, PhD, Abdoul Risgou Ouedraogo, MD, Alfred B Tiono, MD, PhD, Pierre Kaboré, MD, Brice W Bicaba, MD, Msc, Jacques Zoungrana, MD, Adama Sourabié, MD, Souleymane Fofana, MD, Flavien Kaboré, MD, Adama Sanou, MD and Séni Kouanda, MD, PhD

Article Type: Original Research | First Published: February 15, 2021

Many countries have adopted hydroxychloroquine (HCQ) or chloroquine (CQ) and azithromycin (AZ) for the treatment of COVID-19 patients at the beginning of the pandemic and are still using them. The objective of this study was to measure the efficacy of CQ or HCQ and combined with AZ on patients' survival and recovery in Burkina Faso, West Africa. We conducted a hospital-based retrospective cohort study using routine data from all the hospitals involved in the COVID-19 response in Burkina Faso. Al...

 Open Access DOI:10.23937/2469-5858/1510107

The Influence of Cognitive Biases on Healthcare Provider Decision-Making for Patients with Advanced Dementia

Meira Erel, MSc, Esther-Lee Marcus, MD and Freda De Keyser Ganz, PhD

Article Type: Original Article | First Published: February 22, 2021

Decision-making is at the core of clinical practice. According to traditional decision-making theory, the ideal decision maker acts rationally. However, research in cognitive biases demonstrates that decisions are not perfectly rational, and often rely on unconscious processes. This study was conducted to examine cognitive biases of medical teams when making treatment decisions in acute medical conditions for patients with advanced dementia. This was a phenomenological qualitative descriptive st...

 Open Access DOI:10.23937/2572-3235.1510073

Long-Term Survival (27.7 Years) Following IV Antineoplaston Therapy (ANP) in a 36-Year-Old Female with a Progressive Diffuse Intrinsic Pontine Glioma (DIPG)

Stanislaw R Burzynski, MD, PhD, Tomasz Janicki, Gregory S Burzynski and Samuel Beenken

Article Type: Original Article | First Published: February 18, 2021

Long-term survival in Diffuse Intrinsic Pontine Glioma (DIPG) is very rare. The purpose of this report is to detail the early (1988) use of IV Antineoplaston therapy (ANP {A-10 + AS2-1}) and its efficacy in DIPG while presenting the 27.7-year survival of a 36-year-old patient treated with ANP for progressive DIPG. The patient presented in this manuscript was enrolled in BT-3, a Phase II protocol utilizing IV Antineoplastons A10 and AS2-1 (ANP). Tumor response was measured by bi-monthly MRIs of t...

 Open Access DOI:10.23937/2469-5769/1510073

Neonatal Hyperbilirubinemia in Low-Income African Countries

Adam C Gamber, Ethan M Toth, Hendrik J Vreman and Tina M Slusher

Article Type: Review Article | First Published: February 19, 2021

Neonatal hyperbilirubinemia, also known as jaundice, is a significant cause of neonate death and disability in low- and middle-income countries (LMICs). Lack of adequate healthcare facilities, unreliable diagnostic- and treatment equipment, limited parental knowledge, and inconsistent- or absent treatment protocols all contribute to exceptionally high rates of morbidity and mortality especially in Sub-Saharan Africa. This review summarizes the etiology and treatment of neonatal hyperbilirubinemi...

 Open Access DOI:10.23937/2643-4059/1710023

Frequency of Mental Behavioral Disorders in the Emergency Staff during the Care of Patients in the Covid-19 Pandemic

Hernández Gómez Jesús Alejandro, Palomec Antonio Lizbeth, Ruiz Mondragón Alberto and Sánchez Martínez Fátima Alondra

Article Type: Research Article | First Published: February 15, 2021

As the health personnel fight it spread of COVID-19, has acquired information of alterations psychological featured in professionals and technicians of the health that is in contact with patients infected by this virus. Of according to center carried out, the more alterations frequent in a 85% are: Anxiety, depression and Post-traumatic stress. Anxiety is define like of the answers of our mind and body before situations of danger or threat, the it depresses us talk about a group of diseases ment...

 Open Access DOI:10.23937/2378-3419/1410145

Effect of Low Frequency Electrical Current on the Biophysical and Molecular Properties of Cancer Cells

Amit Sengupta, Sanjay Gupta, Asmita Sharda, Hemant S and Arvind Ingle

Article Type: Research Article | First Published: February 25, 2021

Different cells and tissues are known to exhibit varied electromagnetic, electrical and molecular properties. During the repair process, cancer cells as well as normal proliferating cells have higher transmembrane potential than healthy cells. Since the dielectric properties are frequency dependent, applying varying frequencies of current can alter the transmembrane ionic flux of any conductive cell. This, in turn, can generate heat via the joule effect. Thus, it might be possible to alter the t...

 Open Access DOI:10.23937/2378-2951/1410218

Determinants of Spatial Dispersion of P-Wave, QRS Complex, and QT-Interval on 12-Lead Electrocardiogram in Apparently Healthy Adults

Nelson I Oguanobi, Charles U Odenigbo, Ogonna C Oguejiofor, Uchenna C Okonkwo, Ukamaka M Odenigbo3 and Tobenna Agogbua

Article Type: Original Research | First Published: February 19, 2021

The spatial dispersion of P-wave, QRS complex, and QT interval on 12-lead electrocardiogram are related to the electrical instability in cardiac conducting tissues and elevated parameters are associated with increased risk of cardiovascular morbidity and mortality. We sought to evaluate the dispersion of P-wave, QRS complex, and QT interval in healthy adult Nigerians and assess their relationship to age, gender, anthropometric and some physiologic parameters. A total of 128 subjects were recruit...

 Open Access DOI:10.23937/2378-2951/1410217

Utility of Global Longitudinal Strain to Predict Post-Operative Outcomes in Non-Cardiac Surgeries

Chang Joon Park, Liy Si Tan, Pei Huang, Puay Joo Tan, Jason Jia Hao See, MBBS, MRCP

Article Type: Brief Report | First Published: February 13, 2021

Pre-operative echocardiography is performed in select groups of patients for cardiac risk stratification. Many parameters, including Left Ventricular Ejection Fraction (LVEF), are assessed during echocardiography. While many studies have cited association between low LVEF and poor operative outcomes, patients with preserved LVEF might have subtle LV dysfunction that may result in adverse outcome. Studies have described the routine use of global longitudinal strain (GLS) as an alternative measure...

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