ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.



  Last Updated: September 22, 2021

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2377-3634/1410003

Involvement of Regucalcin in Lipid Metabolic Disorder and Diabetes

Masayoshi Yamaguchi

Article Type: Editorial | First Published: October 03, 2014

Obesity and diabetes are currently a major health problem worldwide with growing in prevalence. The incidence of metabolic disease, including type 2 diabetes with obesity, is increased to epidemic levels. Obesity and diabetes induce secondary diseases with various pathophysiologic states, which are important in clinical aspects including cardiovascular disease, neural disturbance, kidney disease, osteoporosis and cancer. Obesity is based on stimulation of adipogenesis. Bone marrow mesenchymal st...

 Open Access DOI:10.23937/2469-570X/1410001

Heterogeneity and Diversity of Cancer Stem Cells in Glioblastoma

N. Sumru Bayin and Dimitris G. Placantonakis

Article Type: Editorial | First Published: August 13, 2014

Glioblastoma (GBM) is the most common and deadly primary brain malignancy, with an annual incidence of over 10,000 new cases in the US and a median survival of 14-16 months. The current standard of care includes surgical resection followed by postoperative radiotherapy and treatment with the alkylating agent temozolamide. Sadly, prognosis for GBM patients has increased only incrementally and rather marginally over the past half century. The fact that GBM has lagged behind other solid malignancie...

 Open Access DOI:10.23937/2378-3648/1410002

Association of XmnI (-158 γG) Polymorphism and Response to Hydroxyurea in Omani S/S and S/β Patients

Hassan SM, Al Muslahi M, Al Riyami M, Bakker E, Harteveld CL and Giordano PC

Article Type: Research Article | First Published: September 26, 2014

Objective: To describe the effect of Hydroxyurea (HU) treatment in Omani Sickle Cell Disease (SCD) patients with different beta-globin gene cluster haplotypes. Materials and methods: A total of 52 cases treated with HU were enrolled in this study. Response to the drug was compared between patients with and without the XmnI polymorphism in the different betaglobin gene cluster haplotypes. We have classified our cohort into three categories: good responders to HU for those patients who had no cr...

 Open Access DOI:10.23937/2378-3001/1/1/1003

Therapeutic Significance of Frequency of Deep Brain Stimulation in Intractable Epilepsy

Alok Gupta and Harinder Jaseja

Article Type: Letter to Editor | First Published: September 30, 2014

Deep brain stimulation (DBS) is emerging as a viable alternative therapy in intractable epilepsy (IE), and although the exact mechanism and electrophysiology of its action remain elusive, some neuroscientists even believe that DBS may in near future become a first line treatment for the patients with IE who are not suitable candidates for epilepsy brain surgery. In addition to the exact placement of electrodes in the target site, the successful outcome of DBS depends largely upon correct choice ...

 Open Access DOI:10.23937/2378-3001/1/1/1002

Pelizaeus-Merzbacher Disease: An Inherited Leukodystrophy Natural History Studies in Understanding Neurogenetic Disorders

Jeremy J. Laukka

Article Type: Editorial | First Published: September 29, 2014

More than a century ago, in 1885 Friedrich Pelizaeus, a German Physician first identified a genetic disorder in five boys in a single family with nystagmus, spasticity of the limbs and developmental delay. Twenty-five years later in 1910, Ludwig Merzbacher independently reexamined this family and described further the neuropathology of 14 affected individuals and found that all affected members shared a common ancestor. Together, Pelizaeus and Merzbacher identified the exclusive X-linked inherit...

 Open Access DOI:10.23937/2378-3419/1/1/1005

Squamous Cell Carcinoma and Squamous Differentiation Histologic Variant of Urothelialcarcinoma of Urinary Bladder: Oncological Outcome Following Definitive Surgical Treatment

Mohamed Wishahi, Hossam Elganzoury and Mohamed Badawy

Article Type: Research Article | First Published: September 29, 2014

Objectives: To investigate the impact of variant histologic patterns of urothelialcarcinoma of the bladder on oncological outcomes of patients treated with Radical Cystectomy (RC). Three histologic patterns were evaluated: Urothelial Carcinoma (UC), Squamous Cell Carcinoma (SCC), and urothelial carcinoma with Squamous Differentiation (SqD). Materials and methods: Retrospective archival study included 258 patients treated with RCfor muscle-invasive carcinoma. Data were reviewed in demographic a...

 Open Access DOI:10.23937/2378-3397/1410009

Laparoscopic Resection of a Large Mesenteric Cyst - A Case Report

Willem M Deserno, Jeroen Heemskerk and Kim WFM Lambregts

Article Type: Case Report | First Published: October 03, 2014

Mesenteric cysts are rare lesions occurring in the abdomen. These cystic lesions can be asymptomatic or present with a specific symptoms. The decision whether to perform open or laparoscopic surgery depends on different features of the cystic lesion. If the cyst is thought to be of benign origin, a laparoscopic resection can be performed. We present a case of a young female with a large mesenteric cyst of 28cm, resected with laparoscopic approach....

 Open Access DOI:10.23937/2378-3397/1410008

Analysis of the Results on Perioperative Blood Loss after a Total Knee Arthroplasty Employing Tranexamic Acid Before or After Inflating the Tourniquet

Ana Torres, Mariano Fernandez-Fairen, Daniel Hernandez Vaquero and Jose Sueiro Fernandez

Article Type: Research Article | First Published: September 30, 2014

Introduction: Tranexamic acid has showed its good results reducing blood loss in total knee arthroplasties. It has also probed being cost-effective (red cell concentrate: 350 euros/ TXA vial 3, 05 euros) but it remains not being clear at what time during the surgery we have to administrate it. In this prospective, randomized study, we have investigated the effects of the use of tranexamic acid before or after inflating the tourniquet on blood loss, transfusion needs and thromboembolic complicati...

 Open Access DOI:10.23937/2378-3397/1410007

Renal Transitional Cell Carcinoma: Case report from the Regional Hospital Buea, Cameroon and Review of Literature

Eyongeta DE, Weledji and Enow Orock GE

Article Type: Case Report | First Published: September 29, 2014

Although transitional cell carcinoma is the most common tumour of the renal pelvis, we report the first histologically-confirmed case in our service in a period of about twenty years. The patient is a midaged female African, with no apparent risks for the disease. She presented with the classical sign of the disease (hematuria) and was treated by nephrouretectomy for a pT3N0MX grade II renal pelvic tumour. She is reporting well one year after surgery. The case highlights not only the peculiar di...

 Open Access DOI:10.23937/2378-3397/1410006

Predictors of Survival after Adult to Adult Living Donor Liver Transplantation (A-ALDLT)

Ayman Alsebaey, Maha Lotfy and Emad Hamdy Gad

Article Type: Research Article | First Published: September 26, 2014

Objectives: Adult-to-adult living donor liver transplantation (A-A LDLT) is an effective therapeutic modality to treat patients with end-stage liver disease. The aim of this study was to define the pre-, intra- and post- operative factors that may influence patient outcome. Methods: The data from 161 (A-A LDLT) patients who had operations between 2003 and 2013 were collected and analyzed retrospectively after exclusion of mortality due to intra-operative bleeding. Data were analyzed using uni-...

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New Issues

VOLUME 8, ISSUE 2

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 8 | ISSUE 2 | 2021

VOLUME 8, ISSUE 2

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 8 | ISSUE 2 | 2021

VOLUME 7, ISSUE 1

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 7 | ISSUE 1 | 2021

VOLUME 8, ISSUE 2

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 8 | ISSUE 2 | 2021

VOLUME 7, ISSUE 4

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 7 | ISSUE 4 | 2021

Featured Articles

Clinical Characteristics of Suspected COVID-19 in Pediatric Patients

Heather Yerdon, BS, Lauren Mutter, MD, Rick Tivis, MPH, Trevor Olsen, PhD and Anna Suessman, DO

DOI:10.23937/2474-3674/1510121



A Neural Mobilization Treatment Strategy for Patients with Neurogenic Claudication Related to Degenerative Lumbar Spinal Stenosis: A Prospective Case Series

Reid Gehring, PT, ScD, Joan Potter-Brunet, PT, DPT, Phillip Sizer, PT, PhD, Kerry Gilbert, PT, ScD and Jean-Michel Brismee, PT, ScD

DOI:10.23937/2469-5718/1510191



Spontaneous Proximal Tibiofibular Joint Ganglion Cyst as a Rare Cause of Acute Foot Drop: A Case Report

Nirguna Thalla, MD, MBA, W Daniel White, MD, J Taylor Mansfield, DO, Jason M Souza, MD and Matthew E Miller, MD

DOI:10.23937/2572-3243.1510095



Flow Related Aneurysm in Hemangioblastoma and Literature Review of Hemorrhagic Rate and Management Strategy

Choo Heng Tan, FRCS, Felicia HZ Chua, MBBS, MRCS and Peter Y wang, FRACS

DOI:10.23937/2643-4474/1710068


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin