ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.



  Last Updated: December 05, 2021

ClinMed Archive

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-2951/1410016

Use of Statins in an Australian Elderly Population

Svetla Gadzhanova, Elizabeth Roughead and Jenni Ilomaki

Article Type: Research Article | First Published: December 28, 2014

Background: Statins are the fist drug choice for lowering high cholesterol and are one of the most widely used classes of medicines in Australia. Although well tolerated, some adverse effects are dose and potency dependent to which older people are particularly susceptible. Objective: The aim of this study was to examine the use of statins in elderly Australians, and how usage had changed over time with respect to dose and potency of statin prescribed....

 Open Access DOI:10.23937/2378-2951/1410015

Necrotizing Pancreatitis Causing Acute Focal Pericarditis

William F McIntyre, Andres Enriquez, Kevin Michael and Adrian Baranchuk

Article Type: Case Report | First Published: December 15, 2014

We describe the case of a 39-year old man with acute necrotizing pancreatitis. A twelve-lead electrocardiogram (A) showed signs of pericarditis and a computed tomography of the abdomen showed focal pericardial effusion, confirming the diagnosis....

 Open Access DOI:10.23937/2378-2951/1410014

A Case Report of Immediate Extubation Post Primary PCI in STEMI

Sharan Rufus Ponniah, Pradeepto Ghosh, Nagapradeep Nagajothi, Srinivasa Satti, Kavitha Nidamanuri and Baskar Rajala

Article Type: Case Report | First Published: December 16, 2014

We report a case of immediate extubation following primary percutaneous intervention (PCI) for ST elevation myocardial infarction (STEMI). The optimal timing of extubation following revascularization in STEMI is unclear. Early extubation in this scenario, if feasible has a mortality benefit. Duration of mechanical ventilation following STEMI is a strong predictor of mortality. In this case, we report a scenario of immediate extubation following revascularization, which we believe contributed to ...

 Open Access DOI:10.23937/2378-3672/1410002

Cockroach Allergy, Respiratory Allergic Diseases and Its Immunotherapy

Oner Ozdemir

Article Type: Review Article | First Published: December 31, 2014

Cockroach allergen-derived proteases play a direct role on airway epithelial as well as dendritic cells thru activation of the protease activated receptor (PAR)-2. Cockroach-derived proteases lead to an increased penetration of cockroach allergen thru disturbing airway epithelial integrity, which can activate innate immune cells (e.g., dendritic cells) via binding to Toll-like receptor or C-type lectin receptors. The activated dendritic cells promote the adaptive immune system cells to a Th2 cel...

 Open Access DOI:10.23937/2378-3672/1410001

Polarization of Human THP-1 Macrophages: Link between Adenosine Receptors, Inflammation and Lipid Accumulation

Michael J. Littlefild, Isaac Teboul, Iryna Voloshyna and Allison B. Reiss

Article Type: Research Article | First Published: December 08, 2014

Rationale: Macrophages are key players in inflammation and atherosclerosis. They express surface receptors of different subtypes for the endogenous autocoid adenosine. Macrophages within atherosclerotic lesions attain two clear-cut functional phenotypes M1 (pro-inflammatory) and M2 (immunosuppressive). This study examines the relative expression of adenosine receptors and proteins involved in cholesterol transport in THP-1 human macrophages upon differentiation into M1 and M2 subtypes....

 Open Access DOI:10.23937/2378-3656/1410013

Recurrent Ischemic Strokes as the First Manifestation of A Pancreatic Cancer

Rosaria Renna

Article Type: Case Report | First Published: January 03, 2015

A 56-year-old Caucasian woman presented to the Emergency Department of our hospital with acute headache and a speech disorder characterized by mild aphasia and dysarthria. She had a history of arterial hypertension and nicotism for several years. Neurological evaluation at admission revealed mild motor aphasia and dysarthria (NIHSS: 2). Brain computed tomography (CT) showed two hypodense lesions, in the lef temporal and the right frontal lobes respectively. Results of laboratory tests revealed e...

 Open Access DOI:10.23937/2378-3656/1410012

Monitoring of the Left Recurrent Laryngeal Nerve during Mediastinoscopy is Feasible and Safe

Wolfram Karenovics, Sebastien Guigard, Besa Zenelaj, Marc Licker and Frederic Triponez

Article Type: Research Article | First Published: December 29, 2014

Objective: Left Recurrent Laryngeal Nerve (RLN) palsy is a well known complication of cervical mediastinoscopy and is not infrequent if specifically looked for. Electro-physiological monitoring of the RLN is common practice in thyroid surgery and has greatly improved outcomes. We applied the same technique during cervical video-mediastinoscopy. Patients and methods: Between October 2012 and October 2013 patients undergoing mediastinoscopy were enrolled prospectively for intra-operative monitorin...

 Open Access DOI:10.23937/2378-3648/1410011

Relationship of Mitochondrial DNA Haplogroups with Complex Diseases

Carlos G Urzua-Traslavina, Maria G Moreno-Trevino, Denisse A Martinez-Trevino, Hugo A Barrera-Saldana and Rafael BR Leon-Cachon

Article Type: Review Article | First Published: December 16, 2014

Mitochondria are responsible for energy production in unicellular and multicellular eukaryotes. Apart from their major role in metabolism, mitochondria are involved in many other cellular processes. A new paradigm is needed to understand aging, aging-related illnesses, and complex diseases. Because of the long co-evolution of mitochondria with the cells, subtle variations in the function of these organelles could influence many organ systems. Understanding the extent of this influence will shed ...

 Open Access DOI:10.23937/2378-3648/1410010

Oxidative Stress and the Epigenome in Human Disease

Adriana Arita and Max Costa

Article Type: Review Article | First Published: December 15, 2014

Epigenetics refers to the study of the changes in gene expression that occur without changes in the DNA sequence. There is growing evidence that epigenetic modifications such as changes in the levels of DNA methylation or post-translational histone modifications are involved in the pathogenesis of many human diseases including cancer. Oxidative stress as a result of metabolic or environmental factors leads to excessive production of reactive oxygen species (ROS). ROS plays a role in many human d...

 Open Access DOI:10.23937/2378-3648/1410009

Discordant Disease Course in a Monozygotic Twin Pair with Juvenile Myelomonocytic Leukemia

Silvia Bresolin, Paola De Filippi, Claudia Cagioni, Simone Cesaro, Annamaria Di Meglio, Anna Leszl, Fiorenza Aprili, Chiara Cugno, Chiara Frasson, Marco Zecca, Cesare Danesino and Geertruyte Kronnie

Article Type: Research Article | First Published: December 14, 2014

Juvenile myelomonocytic leukemia is a rare neoplastic disorder occurring in early childhood often showing an aggressive progression. We report a case of a twin pair with concordant JMML but an extremely different disease course. Both twins presented with somatic aberrations of chromosome 7 and mutations in PTPN11. Analysis of sorted BM and PB cell populations revealed the clonal nature of the disease and indicated that genomic aberrations arise from common hematopoietic precursor cells. PTPN11 m...

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New Issues

VOLUME 8, ISSUE 2

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 8 | ISSUE 2 | 2021

VOLUME 8, ISSUE 2

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 8 | ISSUE 2 | 2021

VOLUME 7, ISSUE 1

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 7 | ISSUE 1 | 2021

VOLUME 8, ISSUE 2

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 8 | ISSUE 2 | 2021

VOLUME 7, ISSUE 4

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 7 | ISSUE 4 | 2021

Featured Articles

Clinical Characteristics of Suspected COVID-19 in Pediatric Patients

Heather Yerdon, BS, Lauren Mutter, MD, Rick Tivis, MPH, Trevor Olsen, PhD and Anna Suessman, DO

DOI:10.23937/2474-3674/1510121



A Neural Mobilization Treatment Strategy for Patients with Neurogenic Claudication Related to Degenerative Lumbar Spinal Stenosis: A Prospective Case Series

Reid Gehring, PT, ScD, Joan Potter-Brunet, PT, DPT, Phillip Sizer, PT, PhD, Kerry Gilbert, PT, ScD and Jean-Michel Brismee, PT, ScD

DOI:10.23937/2469-5718/1510191



Spontaneous Proximal Tibiofibular Joint Ganglion Cyst as a Rare Cause of Acute Foot Drop: A Case Report

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DOI:10.23937/2572-3243.1510095



Flow Related Aneurysm in Hemangioblastoma and Literature Review of Hemorrhagic Rate and Management Strategy

Choo Heng Tan, FRCS, Felicia HZ Chua, MBBS, MRCS and Peter Y wang, FRACS

DOI:10.23937/2643-4474/1710068


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

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International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

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International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

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International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

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International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin