Ovarian Stromal Hyperthecosis and Hyperandrogenemia Refractory to Hormonal Suppression
Gregory M Gressel, Natalia Buza, Shirley M McCarthy and Pinar H Kodaman
Article Type: Case Report | First Published: September 26, 2015
Ovarian stromal hyperthecosis (OSH) is an uncommon clinical entity. According to the 2014 WHO classification of gynecologic tumors, it has been documented in one-third of patients older than age 55 years of age in autopsy studies. This disorder usually presents in the second or third decade of life with menstrual irregularity as well as signs of virilization. Presentation in the post-menopausal period is less common, but has been reported....
Bochdalek Diaphragmatic Hernia Complicating Pregnancy in the third Trimester: Case Report
Monica Hernandez-Aragon, Laura Rodriguez-Lazaro, Raquel Crespo-Esteras, Leyre Ruiz-Campo, Ignacio Adiego-Calvo, Jose Manuel Campillos-Maza, Sergio Castan-Mateo
Article Type: Case Report | First Published: August 07, 2015
A 32-year-old primiparous woman was diagnosed of diaphragmatic hernia at 29 weeks' gestation and transferred to our hospital. Initially, gastrointestinal symptoms mimicked pathology related to pregnancy, but failure of conservative measures led to performing imaging tests. It was a Bochdalek hernia containing small bowel loops, colon and omentum but not stomach. She was stabilized, but finally cesarean delivery and hernia repair were performed at 32 weeks because of her symptoms, with a successf...
Adjuvant Radiation Therapy is Feasible in Epidermolysis bullosa: A Case Report
Theodora A Koulis, Colleen Herring, Wendy Smith and Jon-Paul Voroney
Article Type: Case Report | First Published: September 02, 2015
A patient with a severe form of Epidermolysis Bullosa (EB) presented after an above knee amputation and groin dissection for a 57 cm Squamous Cell Sarcinoma (SCC) of the skin and underlying soft tissue of the right leg. Five of 19 nodes were involved with SCC metastases. Standard care would involve adjuvant Radiation Therapy (RT) but RT has historically been avoided in patients with EB who can have severe, non-healing cutaneous and mucosal morbidity from acute RT reactions. A radiation treatment...
Explosive Cutaneous Mucormycosis Requiring Limb Amputation: Case Report and Literature Review
Vikas Patel, Stephen Squires, Tarek Shaath, Daniel R Hinthorn, Garth R Fraga and Rebecca Horvat
Article Type: Case Report | First Published: August 20, 2015
Mucormycosis is a potentially fatal systemic fungal infection. Risk factors include immunosuppression, organ transplantation, and diabetes mellitus. Rhinocerebral mucormycosis is the most common presentation in diabetic patients, whereas pulmonary mucormycosis is the most common presentation in patients with hematologic neoplasms. We describe an immunocompromised leukemia patient with painful ecchymotic plaques on the forearm. Punch biopsy demonstrated angioinvasive mucormycosis and culture grew...
Time Required between Two Positioning Methods for Shoulder Arthroscopy. A Non-Randomized Controlled Study
Xavier Zwiebel, Anne-Marie Bedard, Alexandre Leclerc and Melissa Laflamme
Article Type: Research Article | First Published: August 27, 2015
Shoulder arthroscopy can be performed with the patient either in the lateral decubitus or the beach chair position. Since the advent of the beach chair position, orthopaedic surgeons have been debating which of those two positions is superior. Each one has its own advantages and disadvantages, whether for the ease of setup, the risks and complications, the intraoperative visualization or the joint accessibility....
The Management of GI bleeding after Gastric Bypass Surgery
Riley K Kitamura, Jane Lee and Lester Brian Katz
Article Type: Case Report | First Published: August 15, 2015
A 38 year-old female with a history of psoriatic arthritis on chronic NSAID use, and obesity underwent a RNYGB in 2010. In 2013, she presented to an outsidehospital with massive GI bleed, requiring multiple transfusions and ICU monitoring. Subsequently, she underwent both upper and lower endoscopy, angiography, capsule endoscopy, and exploratory laparotomy-however, the source of her bleed was ultimately never found and her symptoms resolved spontaneously....
Could Accidental Ischemic Attacks Protect Against Subsequent Ischemic Reperfusion Injury?
Mohamed S. A. Mohamed
Article Type: Retrospective Study | First Published: August 20, 2015
Heart failure is the end result of various cardiac diseases that might be of ischemic or non-ischemic etiology. Implantation of ventricular assisting devices has been introduced as a bridge to heart transplantation, when heart failure reaches a critical degree of decompensation. The ischemic background of heart failure was suggested to have a protective effect in comparison to the non-ischemic background, based on the principles of ischemic conditioning....
Stem Cell Transplantation to Treat Severe Refractory Multiple Sclerosis
Athanasia Mouzaki, Marios I Garyfallou and Kokona Chatzantoni
Article Type: Review Article | First Published: August 13, 2015
In severe, drug-resistant Multiple Sclerosis (MS), Stem Cell Transplantation (SCT) was introduced as a treatment option about 20 years ago. Application of autologous SCT is based on the assumption that MS is not inherited in a Mendelian fashion and the auto reactive immune system can be replaced by a healthy one. Allogeneic SCT ensures that all leukocytes are of donor origin, but is applied rarely. Both approaches are fraught with problems resulting, mainly, from the high-intensity pre-transplan...
Family Oriented Care: Opportunities for Health Promotion and Disease Prevention
Diego Garcia-Huidobro and Tai Mendenhall
Article Type: Review Article | First Published: August 31, 2015
Even though life expectancy has increased in industrialized countries, chronic diseases and mental illnesses are continuous health challenges. Thus, new strategies to further improve health must be implemented. Because family contexts are where health behaviors are usually learned, developed, maintained and changed, targeting family systems (rather than individual patients) is an option to further improving the health status of individuals, families, and communities. This article will review pos...
Xerostomia: Understanding the Diagnosis and the Treatment of Dry Mouth
Ilina Ristevska, Rosaria S. Armata, Christina D'Ambrosio, Melissa Furtado, Leena Anand and Martin A. Katzman
Article Type: Review Article | First Published: August 23, 2015
Xerostomia, commonly referred to as dry mouth syndrome, is a result of reduced or absent salivary flow producing mucosal dryness. It can subsequently cause oral discomforts and alterations in taste, cracked and peeling lips, dry nasal passages, and a painful tongue. Its symptoms make tasks such as swallowing, speaking and sleeping difficult and painful, as well as increasing the risk of gum disease and tooth loss through increased formation of plaque and dental caries....