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ClinMed International Library

For the past decade, ClinMed International Library has been at the forefront of publishing cutting-edge research in clinical medicine. Over the last 10 years, we have consistently provided a platform for publishing innovative findings and advancements in medical science.

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.


  Last Updated: October 12, 2024
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2469-5750/1510020

New Insights and Therapeutic Implications in Cutaneous Melanoma

Pinar Ozuguz, Seval Dogruk Kaca and Serap Polat

Article Type: Review Article | First Published: April 11, 2016

Melanoma is a highly aggressive tumour with poor prognosis in the metastatic stage that arises and evolves due to a myriad of genetic and epigenetic events. Among these, the interaction between epigenetic alterations (i.e., DNA methylation, histone modifications, mRNA silencing by miRNAs and nucleosome repositioning) has been recently identified as playing an important role in melanoma development and progression by affecting key cellular pathways such as cell cycle regulation, DNA repair, apopt...

 Open Access DOI:10.23937/2469-5750/1510019

Targeted Prodrug Design for the Treatment of Malignant Melanoma

Marcella Gabrielle Mendes Machado, Paulo Renato Yamasaki, Jean Leandro dos Santos and Chung Man Chin

Article Type: Short Review | First Published: April 04, 2016

Malignant melanoma is a serious health problem once the current chemotherapy exhibits resistance to traditional drugs. Several challenges must be overcome during drug design in order to increase the efficacy and safety of the new drugs. Therefore, the specific chemical release of cytotoxic agents near to the target is an attractive approach to improve the anticancer activity and reduce the systemic toxicity. Herein, this review article describes the advances in the development of targeted prodru...

 Open Access DOI:10.23937/2378-3397/1410040

Comparative Study of Laparoscopic Versus Open Resection of Colorectal Liver Metastasis

Christian Hunnicke Petersen, Peter Norgaard Larsen, Jan Storkholm, Nicolai Aagaard Schultz and Kenneth Hojsgaard Jensen

Article Type: Original Article | First Published: March 30, 2016

Laparoscopic liver resection is gaining increased application in the treatment of colorectal liver metastases (CRLM). The aim of this study is to compare safety and feasibility of minor laparoscopic liver resection vs. open liver resection in patients with CRLM. One hundred and twenty-eight patients who underwent minor resection of CRLM were retrospectively reviewed. Sixty-four consecutive cases of laparoscopic liver resections (LLR) were compared to a matched control group of 64 open liver rese...

 Open Access DOI:10.23937/2378-3516/1410043

Platelet to Lymphocyte Ratio as a Novel Prognostic Marker in Male Patients with Chronic Obstructive Pulmonary Disease

Sezgi Sahin Duyar, Yalcin Solak, Dilek Tekis, Jale Karakaya, Ferit Kuscu and Asuman Erarslan

Article Type: Original Article | First Published: March 31, 2016

Neutrophil to lymphocyte ratio(NLR) and platalet to lymphocyte ratio (PLR) are recently defined novel inflammatory markers which are readily available. Their prognostic signifigance has been shown for a number of inflammatory diseases. A recent study evaluated the role of NLR in patients with chronic obstructive pulmonary disease(COPD). Thus, we aimed to investigate the relations between NLR, PLR and severity of COPD in male patients who had stable disease....

 Open Access DOI:10.23937/2469-5807/1510030

Reduced and Thinned Elastic Fibers in Skin Tag

Ahmed Abdullah Alhumidi

Article Type: Mini Review | First Published: March 29, 2016

This is a retrospective study in which thirty histopathological specimens of fibroepithelial polyp (skin tag) were examined. Their paraffin blocks were collected from the archives of the Pathology Department, king khalid University hospital, Riyadh, Saudi Arabia, during the period from 2010 to 2012. Age of the patient, sex, and site, of the lesions as well as type of skin tag were recorded. Sections from each paraffin block were cut by a microtome at 5-micron thickness, stained with hematoxylin ...

 Open Access DOI:10.23937/2572-4215.1510006

The Disconnect between Treatment Outcome Data and Reimbursement for the Treatment of Anorexia Nervosa

David M. Garner, Meggan Desmond, Julie Desai and Jan Lockert

Article Type: Research Article | First Published: April 06, 2016

A major problem plaguing the discussion of insurance reimbursement for the treatment of anorexia nervosa is the apparent gap between research on variables associated with outcome and the formulas used for reimbursement. Outside of the mental health world, insurance coverage is driven by advanced analytics and actuarial data. However, in calculating insurance reimbursement for the treatment of anorexia nervosa, actuarial data associated with short-term and long-term outcomes are not utilized. Ins...

 Open Access DOI:10.23937/2378-3419/3/2/1052

Relation between Thyroid Disease and Breast Cancer

Ersin Turan and Baris Sevinc

Article Type: Original Article | First Published: March 31, 2016

Benign thyroid nodules are most common surgically treated endocrine disorder. Breast cancer is the most common cancer type among women. In the recent study, we aimed to detect the relation between breast cancer and benign thyroid nodules. The patients operated because of breast cancer and have a definite diagnosis with pathological evaluation were included in this prospective study....

 Open Access DOI:10.23937/2378-346X/1410049

Routes of Oxidative Stress in Age-Related Macular Degeneration

Manresa N, Mulero J, Losada M and Zafrilla P

Article Type: Review Article | First Published: May 07, 2016

The pathogenic mechanism of AMD is poorly understood. The ROS and nitrogen species produced during stress may damage crucial biomolecules of the retinal pigment epithelium (RPE) cells. There is a strong relation between stress oxidative and inflammatory response in the pathology of the AMD. Actually, there are many routes of oxidative stress related with AMD but the most representative are: autophagy/heterophagy, apoptosis, and iron, DNA and antioxidant enzymes. Autophagy is a cellular housekeep...

 Open Access DOI:10.23937/2378-3001/3/2/1044

Trigeminal Neuropathy as a Relapse in Behcet Disease

Goncalo Cacao, Isabel Moreira, Jose Eduardo Alves, Fatima Farinha and Ernestina Santos

Article Type: Case Report | First Published: March 29, 2016

A 49 years old woman, diagnosed with Neuro-Behcet, was admitted with complains of numbness, aching and periods of electric shock-like pain in right side of the face. Associated with painful oral ulcers, anorexia, nausea and gait instability. Neurological examination revealed dysesthesia on right trigeminal nerve territory, horizontal-rotatory nistagmus on horizontal gaze bilateral with fast phase to the right and tandem instability. Brain MRI revealed new lesions. It was assumed a rhombencephali...

 Open Access DOI:10.23937/2378-3001/3/2/1043

Neuromyelitis Optica Spectrum Disorder in A Ninety-year-old Woman. A Case Report

Romero-Delgado Fernando, Cuello Juan-Pablo, Garcia-Dominguez Jose-Manuel, Higueras-Hernandez Yolanda, Goicochea-Briceno Haydee, Guzman-de-Villoria Juan Adan and Martinez-Gines Maria-Luisa

Article Type: Case Report | First Published: March 28, 2016

Neuromyelitis Optica (NMO) is an inflammatory demyelinating, necrotizing disease of the central nervous system, with a predilection for the optic nerves and spinal cord. Clinical, radiological and immunopathological characteristics distinguish it from multiple sclerosis (MS). Recently, new diagnostic criteria have been published, and the terms NMO and neuromyelitis optica spectrum disorder (NMOSD) have been unified, allowing a diagnosis of NMOSD on clinical grounds or on anti-AQP4 antibody statu...

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All Indexed Journals

Partnered with ICI World of Journals. Check the Index Copernicus Values of ClinMed Journals

ClinMed Journals Index Copernicus Values

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Sports and Exercise Medicine: 91.84

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

International Journal of Clinical Cardiology: 89.24

Journal of Dermatology Research and Therapy: 89.34



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New Issues

VOLUME 10

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 10
VOLUME 10

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 10
VOLUME 9

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 9
VOLUME 10

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 10
VOLUME 9

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 9

Featured Articles

Treatment of a Lacerated Aneurysmal Neck during Surgical Clipping of Usual Saccular Cerebral Aneurysms: Two Illustrative Cases

Hideki Nakajima, MD*, Morio Takasaki, MD, Taku Hongo, MD, Katsuma Iwaki, MD, PhD, Ryota Miyake, MD and Yasuhiro Fujimoto, MD

DOI: 10.23937/2643-4474/1710160



Pathophysiology of the Skin in Type 1 and Type 2 Diabetes and Emerging Therapeutic Opportunities

Priyanka Prabhakar Poonja, MBBS,* and Flora Kiss, MD, PhD

DOI: 10.23937/2377-3634/1410182



Colovesical Fistula Secondary to Colorectal Adenocarcinoma: A Diagnostic and Therapeutic Challenge

Abdulrahman Alquliti, Abdullah Salah Alharbi*, Muhammad Ahmad Alghamdi, Abdulaziz Albalawi, Hamad Alakrash and Abdullah Alghamdi

DOI: 10.23937/2469-5742/1510094



High Grade Glioma Surgery, Using 5-Aminolevulinic Acid and Its Effect on Extent of Resection: Early Data from a Single Canadian Center Experience

Felix LeBlanc#, Lyndon Boone#, Timothy Noble, Jane Burns, Dhany Charest, Maxime Richer and Antonios El Helou*

DOI: 10.23937/2643-4474/1710159


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Respiratory and Pulmonary Medicine Editor-in-chief: Prof. Shufeng Zhou

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin