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 Commentary 


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Published Date
September 19, 2018

Vol. 4, Issue 2

Chromatin Lipid Microdomains

Carmela Conte, Michela Codini and Elisabetta Albi

Corresponding author: Elisabetta Albi, Department of Pharmaceutical Science, University of Perugia, Perugia, Italy.

In nuclear membrane, the precise relation among these lipids is responsible for maintenance of normal fluidity in no stimulated cells. During rat liver regeneration, in which the cells are stimulated to proliferate, lipid composition and consequently fluidity of nuclear membranes modify, favoring an increase of mRNA transport that

Citation: Conte C, Codini M, Albi E (2018) Chromatin Lipid Microdomains. Int J Pathol Clin Res 4:075.



 Research Article 


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Published Date
September 14, 2018

Vol. 4, Issue 2

The Study of Ductal Carcinoma In Situ (DCIS) with Microinvasion Using Myoepithelial Markers

Sana Firdous, Anjaneyulu, Daphne Fonseca, Sudha Murthy, Sundaram Challa and CK Naidu

Corresponding author: Dr. Sana Firdous, Resident, Basavatarakam Indo American and Cancer Institute, Sayanna Residency, Flat no.301, Krishna Nagar Colony, Opposite Gandhi Hospital, Hyderabad, Telangana, India, Tel: 00918686922063.

DCIS is a premalignant condition characterized by proliferation of neoplastic cells within the ducts with intact myoepithelial cell layer and when there is a breach in myoepithelial cell layer it indicates invasion and in both these condition treatment protocols and prognosis is different. Myoepithelial markers can be used to identify breach and hence invasion.

Citation: Firdous S, Anjaneyulu, Fonseca D, Murthy S, Challa S, et al. (2018) The Study of Ductal Carcinoma In Situ (DCIS) with Microinvasion Using Myoepithelial Markers. Int J Pathol Clin Res 4:074.



 Case Report 


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Published Date
September 03, 2018

Vol. 4, Issue 2

Ambiguity in Diagnosis of Extra-Pulmonary Breast Tuberculosis as Breast Abscess/Duct Ectasia

Hemlata Panwar, T Santosh, Bharti Kumari, Vandita Singh and RK Ramchandani

Dr. T Santosh, PDCC Dermatopathology, Department of Pathology and Lab Medicine, All India Institutes of Medical Sciences (AIIMS), Bhopal, MP, India, Tel: 08895495670.

Tubercular mastitis is a great masquerader and is an extremely rare entity as extra-pulmonary tuberculosis even in endemic countries like India and incidence accounts for 4% of breast lesions. We report a case of primary TB of breast in a elderly female presenting as diffuse upper left breast lump with indurated and ulcerated overlying skin along with retraction of nipple. Clinically suspicion was of abscess and duct ectasia. Fine needle aspiration cytology (FNAC) of breast lump with touch imprint smears was done.

Citation: Panwar H, Santosh T, Kumari B, Singh V, Ramchandani RK (2018) Ambiguity in Diagnosis of Extra-Pulmonary Breast Tuberculosis as Breast Abscess/Duct Ectasia. Int J Pathol Clin Res 4:073.



 Letter To Editor 


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Published Date
September 03, 2018

Vol. 4, Issue 2

Malignant Melanoma Arising of Gland Pigmentary Disorders

Vitorino Modesto dos Santos and Lister Arruda Modesto dos Santos

Prof. Dr. Vitorino Modesto dos Santos, Armed Forces Hospital, Estrada do Contorno do Bosque, Cruzeiro Novo, CEP 70658-900, Brasília-DF, Brazil, Tel: #55-61-39662103, Fax: #55-61-32331599.

Malignant melanoma represents up to 5% of cutaneous cancers, but up to 75% of the cases have fatal outcomes. The early diagnosis and prompt treatment can reduce the impressive mortality rate of this ominous malignancy. Both amelanotic and melanotic melanoma may be associated with delayed clinical suspicion and late diagnosis, harmful occurrence that may be related to lack of awareness of health care workers or unusual site of the tumors. The manuscripts herein commented described exceeding rare presentations of this challenging malignant tumor. The purpose is to enhance the suspicion index of primary health care workers about uncommon clinical features.

Citation: dos Santos VM, dos Santos LAM (2018) Malignant Melanoma Arising of Gland Pigmentary Disorders. Int J Pathol Clin Res 4:072.



 Case Report 


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Published Date
August 29, 2018

Vol. 4, Issue 2

Bilateral Vulvar Ectopic Breast Tissue in a 38-Year-Old Woman Who is Breastfeeding: Case Report and Review of the Literature

Maria Sol Peremateu, Maria Lucrecia Absi, Maria Celeste Sluga, Alejandra Wernicke and Claudia Marchitelli

Claudia Marchitelli, MD, Gynecology Department, Hospital Italiano of Buenos Aires, Avenida Pavon 4239, Zip code C1253ABA, Buenos Aires, Argentina, Tel: +5411-4445-4997.

Though long considered to be ectopic breast tissue representing the caudal remnants of the milk ridges, anogenital mammary-like glands are nowadays believed to represent a normal constituent of the anogenital area. Lesions involving these glands are histologically similar to their mammary counterparts and can develop the same benign and malignant tumors as the normally located breast. Because of their infrequent presentation, they represent a challenge for physicians.

Citation: Peremateu MS, Absi ML, Sluga MC, Wernicke A, Marchitelli C (2018) Bilateral Vulvar Ectopic Breast Tissue in a 38-Year-Old Woman Who is Breastfeeding: Case Report and Review of the Literature. Int J Pathol Clin Res 4:071.



 Case Report 


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Published Date
August 23, 2018

Vol. 4, Issue 2

A 68-Year-Old Man with Apathetic Hyperthyroidism and Lung Cancer

Vitorino Modesto dos Santos and Lister Arruda Modesto dos Santos

Prof. Dr. Vitorino Modesto dos Santos, Armed Forces Hospital. Estrada do Contorno do Bosque, Cruzeiro Novo, CEP 70658-900, Brasília-DF, Brazil, Tel: #55-61-39662103, Fax: #55-61-32331599.

The case study of a non-small cell lung carcinoma confirmed by complete necropsy study is reported in an old man with apathetic hyperthyroidism, atrial fibrillation and heart failure. The authors emphasize diagnostic challenges related to effects of hyperthyroidism on nutritional status versus under nutrition caused by unsuspected development of a coexistent malignancy.

Citation: dos Santos VM, dos Santos LAM (2018) A 68-Year-Old Man with Apathetic Hyperthyroidism and Lung Cancer. Int J Pathol Clin Res 4:070.



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International Journal of Blood Research and Disorders   (ISSN: 2469-5696)
International Journal of Brain Disorders and Treatment (ISSN: 2469-5866)
International Journal of Cancer and Clinical Research (ISSN: 2378-3419)
International Journal of Clinical Cardiology (ISSN: 2469-5696)
Journal of Clinical Gastroenterology and Treatment (ISSN: 2469-584X)
Clinical Medical Reviews and Case Reports (ISSN: 2378-3656)
Journal of Dermatology Research and Therapy (ISSN: 2469-5750)
International Journal of Diabetes and Clinical Research (ISSN: 2377-3634)
Journal of Family Medicine and Disease Prevention (ISSN: 2469-5793)
Journal of Genetics and Genome Research (ISSN: 2378-3648)
Journal of Geriatric Medicine and Gerontology (ISSN: 2469-5858)
International Journal of Immunology and Immunotherapy (ISSN: 2378-3672)
International Journal of Medical Nano Research (ISSN: 2378-3664)
International Journal of Neurology and Neurotherapy (ISSN: 2378-3001)
International Archives of Nursing and Health Care (ISSN: 2469-5823)
International Journal of Ophthalmology and Clinical Research (ISSN: 2378-346X)
International Journal of Oral and Dental Health (ISSN: 2469-5734)
International Journal of Pathology and Clinical Research (ISSN: 2469-5807)
International Journal of Pediatric Research (ISSN: 2469-5769)
International Journal of Respiratory and Pulmonary Medicine (ISSN: 2378-3516)
Journal of Rheumatic Diseases and Treatment (ISSN: 2469-5726)
International Journal of Sports and Exercise Medicine (ISSN: 2469-5718)
International Journal of Stem Cell Research & Therapy (ISSN: 2469-570X)
International Journal of Surgery Research and Practice (ISSN: 2378-3397)
Trauma Cases and Reviews (ISSN: 2469-5777)
International Archives of Urology and Complications (ISSN: 2469-5742)
International Journal of Virology and AIDS (ISSN: 2469-567X)
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