The Pivotal Role of Microbiota in Obesity
L. Bonfrate and P. Portincasa
Article Type: Editorial | First Published: February 25, 2015
In general, obesity is a complex disease that results from the interplay between several determinants. From time to time, a role for host genetics, environment, biological factors, pregnancy and lactation history in mothers, social and cultural influence, and imbalance between energy intake and expenditure has been advocated. Dietary factors modulate the composition of the gut microbiota....
Anti-Obesity Drugs: A Necessary Part of Treatment
Raquel Cristina Lopes Assis Coelho
Article Type: Editorial | First Published: January 29, 2015
Worldwide obesity prevalence has nearly doubled since 1980. Obesity is reaching epidemic proportions worldwide and it is correlated with various comorbidities, among which the most relevant are diabetes mellitus, arterial hypertension, and cardiovascular diseases. Obesity management is a modern challenge because of the rapid evolution of unfavorable lifestyles. Due to numerous co-morbidities, obesity represents a serious health and socioeconomic problem worldwide....