PTSD is a mental health condition that can develop in some individuals who have experienced or witnessed a traumatic or life-threatening event. Previously, we identified a combination of blood biomarkers to differentiate controls from a PTSD cohort. This biomarker model could be used to diagnose and monitor treatment of PTSD, both behavioural and pharmacological. ...

The neurobiological features of Post-Traumatic Stress Disorder (PTSD), a debilitating psychiatric condition triggered by exposure to traumatic events, are associated with enigmatic pathological mechanisms which are becoming clearer as the library of associated literature increases. This article considers the clinical features of PTSD, the neural circuitry at work, and some of the genetic and epigenetic factors contributing to PTSD risk. ...