International Journal of

Pediatric ResearchISSN: 2469-5769


 Open Access DOI:10.23937/2469-5769/1510047

D-Penicillamine in the Neonatal Period: Past (!), Present (!?) and Future (?!)

Lajos Lakatos

Article Type: Case Report | First Published: December 01, 2018

D-penicillamine (D-PA) was first recognized as a potential benefit for neonatal hyperbilirubinemia (NHBI) caused by hemolytic diseases of the newborn infant or immaturity of UDP-glucuronyltransferase enzyme. During a long-term follow up study there was a remarkedly low incidence of retrolental fibroplasia (RLF) in the infants treated with D-PA in their neonatal period. Then, all infants < 1500 g birthweight were treated with D-PA to prevent retinopathy of prematurity (ROP). This preventive inter...

 Open Access DOI:10.23937/2469-5769/1510046

Associations between Maturity Status and Dietary Intake in Austrian Adolescents

Clemens Drenowatz and Klaus Greier

Article Type: Research Article | First Published: November 19, 2018

Dietary intake plays an important role in the development and health of children and adolescents. Puberty is a particularly vulnerable period due to the increased nutrient demands associated with growth. This age range has also been associated with various changes in health behavior. While several studies have examined the influence of the social and built environment on dietary habits during adolescence, there remains limited research on the association between biological maturation and eating ...

 Open Access DOI:10.23937/2469-5769/1510045

Acute Necrotizing Encephalopathy in Children: A Case Report and Literature Review

Ping Yuan and Min Zhong

Article Type: Case Report | First Published: November 16, 2018

Acute necrotizing encephalopathy (ANE) is a rare clinical-imaging syndrome with unknown etiology, characterized by acute fulminant severe encephalopathy and brain damage with multifocal symmetry. ANE has no specific clinical symptoms and signs, similar to common encephalitis or encephalopathy symptoms. The characteristic brain imaging examination is diagnostically significant. To date, no specific treatment for ANE is available and the prognosis is poor. Here, we reported a typical case of ANE i...

 Open Access DOI:10.23937/2469-5769/1510044

Childhood Fever Knowledge and Management: A Case of Mothers with Children under Five Years

Reindolf Anokye, Rita Amihere, Patience Abbiaw, Enoch Acheampong, Naomi Gyamfi and Amy Budu-Ainooson

Article Type: Original Article | First Published: November 15, 2018

Most childhood ailments often present with fever which account for the most common reasons why parents seek medical care for their children; particularly, the under-five children. The study aimed to assess the mothers' knowledge of fever in their under-five children and how this is managed at home. This was a descriptive designed study that used a simple random sampling technique to select 100 participants who were mothers of under-five children who presented to the Kwahu Government Hospital, At...

 Open Access DOI:10.23937/2469-5769/1510043

A Novel ATP1A2 Mutation in Pediatric Hemiplegic Migraine

Christopher J Butler and Andrew Mallick

Article Type: Case Report | First Published: November 02, 2018

Migraine is a common pediatric disorder presenting with unilateral frontal headache. Hemiplegic migraine is a rare and clinically challenging subtype of migraine with aura. There are two different subtypes of hemiplegic migraines; they can occur as either sporadic or familial forms. Recently our understanding of the genetics underlying hemiplegic migraine has rapidly evolved. Familial hemiplegic migraine has been associated with pathogenic mutations in three independent genes. Migraine is a comm...

 Open Access DOI:10.23937/2469-5769/1510042

Birthweight and Gestational Age: Early Life Management Strategy to Population Health for Non-Communicable Diseases

Issa Al Salmi and Suad Hannawi

Article Type: Research Article | First Published: October 31, 2018

Non-communicable diseases (NCD) are rising throughout the globe over the last few decades. Developing countries bear the worse burden of these NCD. Similarly, low birthweight is increasing around the world where most of this prevalence commonly seen in the developing countries but as well in the well-developed countries where advancement of health care managed to increase the survival of the very low birthweight babies. In recent years, there has been great interest in the early development of t...

 Open Access DOI:10.23937/2469-5769/1510041

Hemophagocytic Lymphohistiocytosis Secondary to H1N1 Pneumonia: A Case Report

Manoj D, Vinayaka HS and Basavaraj GV

Article Type: Case Report | First Published: October 24, 2018

Hemophagocytic Lymphohistiocytosis (HLH) describes a clinical syndrome of hyperinflammation resulting in uncontrolled and ineffective immune response. It may be primary or secondary HLH. Primary HLH is better defined as "genetic" encompassing both the familial hemophagocytic lymphohistiocytosis (FHL) and also HLH occurring in association with Chediak-Higashi syndrome, Griscelli syndrome type 2 and X-linked lymphoproliferative disorder. FHL is inherited as an autosomal recessive manner. The incid...

 Open Access DOI:10.23937/2469-5769/1510040

Histopathological Fate in the Inguinal Hernia Sac in the Children

Mustafa Yasar Ozdamar

Article Type: Original Research | First Published: October 19, 2018

Obliteration of the processus vaginalis during the fetal growth begins with a transient decrease in sympathetic tonus and then ends with smooth muscle cells (SMCs) undergoing apoptosis. Otherwise, an inguinal hernia (IH) occurs due to the defective obliteration. Although the mechanism in the formation of an inguinal hernia has been elucidated by many investigations, it has not been investigated whether proliferation in the IH sac cells which would lead to the benign or malignant process. In this...

 Open Access DOI:10.23937/2469-5769/1510039

Pediatric Nature of Enteric Fever with Emerging Antibiogram: A Cross Sectional Study

Sameer Sarswat, Mithilesh Kumar and Raju Gupta

Article Type: Original Article | First Published: October 05, 2018

Typhoid fever is a life-threatening systemic infection occurring in developing countries like India. The presenting signs and symptoms of typhoid fever in children differ from adults. Some studies indicate reemergence of sensitivity of Salmonella with chloramphenicol. 164 children between 1-12 years of age with suspected enteric fever were enrolled in the study. Out of these, 73 patients were diagnosed as enteric fever and clinical features were compared among different age groups. Antibiotic se...

 Open Access DOI:10.23937/2469-5769/1510038

Impact of Double Volume Exchange Transfusion on Biochemical Parameters in Neonatal Hyperbilirubinemia

Mohd Ibrahim Wani, Mudasir Nazir, Roumissa Lone, Mohd Rafiq, Syed Wajid Ali and Bashir Ahmad Charoo

Article Type: Research Article | First Published: October 05, 2018

Almost 60% of normal healthy term babies and 80% of preterm babies develop visible jaundice in the first week of life. Although the outcome of the majority is benign, newborns with untreated severe hyperbilirubinemia can develop short and long-term sequelae of bilirubin encephalopathy. This study was designed to evaluate the impact of exchange transfusion on various biochemical parameters and to assess the need for routine calcium gluconate supplementation during the procedure....

 Open Access DOI:10.23937/2469-5769/1510037

Lifestyle, Diet and Body Mass Index in Offspring of Women with Pregestational and Gestational Diabetes

Nurah M Hammoud, Harold W de Valk, Lenie van Rossem, Geertje W Dalmeijer, Douwe H Biesma, Jan M Wit, Maarten Rijpert and Gerard HA Visser

Article Type: Research Article | First Published: October 05, 2018

Offspring from women with diabetes have an increased risk for childhood obesity, which may be related to the abnormal intrauterine environment, genetic imprinting or current diet and lifestyle. We analyzed whether diet and lifestyle differ between offspring from women with either type 1, type 2 or gestational diabetes. We collected completed questionnaires from parents of 51 offspring from women with type 1 diabetes (ODM1), 21 of women with type 2 diabetes (ODM2) and 87 of women with gestational...

 Open Access DOI:10.23937/2469-5769/1510036

Impact of Exclusive Breastfeeding on Digital Sucking in Children Attending the Children's Outpatient Department of University of Uyo Teaching Hospital, Uyo

Oloyede Iso Precious and Okpokowuruk Frances Sam

Article Type: RESEARCH ARTICLE | First Published: September 12, 2018

Sucking of the digits is the most common oral habit found in children. It is a form of non-nutritive sucking which appears to be influenced by various factors. When the habit becomes prolonged, it can lead to both dental and hand complications. Breastfeeding is one of the factors known to be protective against this habit in children. Therefore, the aim of this study was to find out the prevalence of digital sucking in our environment and the influence of breastfeeding/exclusive breast feeding in...

 Open Access DOI:10.23937/2469-5769/1510035

Congenital Cytomegalovirus Infection Presenting as Severe Conjugated Hyperbilirubinemia on First Day of Life

Aaradhana Singh and Ravi Sachan

Article Type: Case Report | First Published: July 12, 2018

Congenital Cytomegalovirus infection (CMV) has varied presentations ranging from asymptomatic to involvement of multiple organ systems like central nervous system, gastrointestinal, hepatic and hematopoietic. Jaundice is a manifestation of congenital CMV presenting as neonatal hepatitis or cholestasis jaundice. We report a case of severe conjugated hyperbilirubinemia presenting on the first day of life that was diagnosed as a case congenital CMV on further workup....

Volume 4
Issue 2